TY - JOUR AU - Brenner, H. AU - Kloor, M. AU - Pox, C. P. PY - 2014 DA - 2014// TI - Colorectal cancer JO - Lancet. VL - 383 UR - https://doi.org/10.1016/S0140-6736(13)61649-9 DO - 10.1016/S0140-6736(13)61649-9 ID - Brenner2014 ER - TY - JOUR AU - Song, M. AU - Garrett, W. S. AU - Chan, A. T. PY - 2015 DA - 2015// TI - Nutrients, foods, and colorectal cancer prevention JO - Gastroenterology VL - 148 UR - https://doi.org/10.1053/j.gastro.2014.12.035 DO - 10.1053/j.gastro.2014.12.035 ID - Song2015 ER - TY - JOUR AU - Network, C. G. A. PY - 2012 DA - 2012// TI - Comprehensive molecular characterization of human colon and rectal cancer JO - Nature. VL - 487 UR - https://doi.org/10.1038/nature11252 DO - 10.1038/nature11252 ID - Network2012 ER - TY - JOUR AU - Guinney, J. AU - Dienstmann, R. AU - Wang, X. AU - Reynies, A. AU - Schlicker, A. AU - Soneson, C. PY - 2015 DA - 2015// TI - The consensus molecular subtypes of colorectal cancer JO - Nat Med VL - 21 UR - https://doi.org/10.1038/nm.3967 DO - 10.1038/nm.3967 ID - Guinney2015 ER - TY - JOUR AU - Vogelstein, B. AU - Kinzler, K. W. PY - 2004 DA - 2004// TI - Cancer genes and the pathways they control JO - Nat Med VL - 10 UR - https://doi.org/10.1038/nm1087 DO - 10.1038/nm1087 ID - Vogelstein2004 ER - TY - JOUR AU - Sousa, E. M. F. AU - Wang, X. AU - Jansen, M. AU - Fessler, E. AU - Trinh, A. AU - Rooij, L. P. PY - 2013 DA - 2013// TI - Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions JO - Nat Med VL - 19 UR - https://doi.org/10.1038/nm.3174 DO - 10.1038/nm.3174 ID - Sousa2013 ER - TY - JOUR AU - Patai, A. V. AU - Molnar, B. AU - Tulassay, Z. AU - Sipos, F. PY - 2013 DA - 2013// TI - Serrated pathway: alternative route to colorectal cancer JO - World J Gastroenterol VL - 19 UR - https://doi.org/10.3748/wjg.v19.i5.607 DO - 10.3748/wjg.v19.i5.607 ID - Patai2013 ER - TY - JOUR AU - Ensari, A. AU - Bosman, F. T. AU - Offerhaus, G. J. PY - 2010 DA - 2010// TI - The serrated polyp: getting it right! JO - J Clin Pathol VL - 63 UR - https://doi.org/10.1136/jcp.2010.077222 DO - 10.1136/jcp.2010.077222 ID - Ensari2010 ER - TY - JOUR AU - Leggett, B. AU - Whitehall, V. PY - 2010 DA - 2010// TI - Role of the serrated pathway in colorectal cancer pathogenesis JO - Gastroenterology. VL - 138 UR - https://doi.org/10.1053/j.gastro.2009.12.066 DO - 10.1053/j.gastro.2009.12.066 ID - Leggett2010 ER - TY - JOUR AU - Noffsinger, A. E. PY - 2009 DA - 2009// TI - Serrated polyps and colorectal cancer: new pathway to malignancy JO - Annu Rev Pathol VL - 4 UR - https://doi.org/10.1146/annurev.pathol.4.110807.092317 DO - 10.1146/annurev.pathol.4.110807.092317 ID - Noffsinger2009 ER - TY - JOUR AU - Sakamoto, N. AU - Feng, Y. AU - Stolfi, C. AU - Kurosu, Y. AU - Green, M. AU - Lin, J. PY - 2017 DA - 2017// TI - BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis JO - Elife. VL - 6 UR - https://doi.org/10.7554/eLife.20331 DO - 10.7554/eLife.20331 ID - Sakamoto2017 ER - TY - JOUR AU - Nakanishi, Y. AU - Diaz-Meco, M. T. AU - Moscat, J. PY - 2019 DA - 2019// TI - Serrated colorectal Cancer: the road less travelled? JO - Trends Cancer VL - 5 UR - https://doi.org/10.1016/j.trecan.2019.09.004 DO - 10.1016/j.trecan.2019.09.004 ID - Nakanishi2019 ER - TY - JOUR AU - Ursem, C. AU - Atreya, C. E. AU - Loon, K. PY - 2018 DA - 2018// TI - Emerging treatment options for BRAF-mutant colorectal cancer JO - Gastrointest Cancer VL - 8 ID - Ursem2018 ER - TY - JOUR AU - Sousae Melo, F. AU - Kurtova, A. V. AU - Harnoss, J. M. AU - Kljavin, N. AU - Hoeck, J. D. AU - Hung, J. PY - 2017 DA - 2017// TI - A distinct role for Lgr5(+) stem cells in primary and metastatic colon cancer JO - Nature. VL - 543 UR - https://doi.org/10.1038/nature21713 DO - 10.1038/nature21713 ID - Sousae Melo2017 ER - TY - JOUR AU - Ricci-Vitiani, L. AU - Lombardi, D. G. AU - Pilozzi, E. AU - Biffoni, M. AU - Todaro, M. AU - Peschle, C. PY - 2007 DA - 2007// TI - Identification and expansion of human colon-cancer-initiating cells JO - Nature. VL - 445 UR - https://doi.org/10.1038/nature05384 DO - 10.1038/nature05384 ID - Ricci-Vitiani2007 ER - TY - JOUR AU - Visioli, A. AU - Giani, F. AU - Trivieri, N. AU - Pracella, R. AU - Miccinilli, E. AU - Cariglia, M. G. PY - 2019 DA - 2019// TI - Stemness underpinning all steps of human colorectal cancer defines the core of effective therapeutic strategies JO - EBioMedicine. VL - 44 UR - https://doi.org/10.1016/j.ebiom.2019.04.049 DO - 10.1016/j.ebiom.2019.04.049 ID - Visioli2019 ER - TY - JOUR AU - Dai, Z. AU - Coker, O. O. AU - Nakatsu, G. AU - Wu, W. K. K. AU - Zhao, L. AU - Chen, Z. PY - 2018 DA - 2018// TI - Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers JO - Microbiome. VL - 6 UR - https://doi.org/10.1186/s40168-018-0451-2 DO - 10.1186/s40168-018-0451-2 ID - Dai2018 ER - TY - JOUR AU - Iida, N. AU - Dzutsev, A. AU - Stewart, C. A. AU - Smith, L. AU - Bouladoux, N. AU - Weingarten, R. A. PY - 2013 DA - 2013// TI - Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment JO - Science. VL - 342 UR - https://doi.org/10.1126/science.1240527 DO - 10.1126/science.1240527 ID - Iida2013 ER - TY - JOUR AU - Feng, Q. AU - Liang, S. AU - Jia, H. AU - Stadlmayr, A. AU - Tang, L. AU - Lan, Z. PY - 2015 DA - 2015// TI - Gut microbiome development along the colorectal adenoma-carcinoma sequence JO - Nat Commun VL - 6 UR - https://doi.org/10.1038/ncomms7528 DO - 10.1038/ncomms7528 ID - Feng2015 ER - TY - JOUR AU - Tilg, H. AU - Adolph, T. E. AU - Gerner, R. R. AU - Moschen, A. R. PY - 2018 DA - 2018// TI - The intestinal microbiota in colorectal Cancer JO - Cancer Cell VL - 33 UR - https://doi.org/10.1016/j.ccell.2018.03.004 DO - 10.1016/j.ccell.2018.03.004 ID - Tilg2018 ER - TY - JOUR AU - Panebianco, C. AU - Andriulli, A. AU - Pazienza, V. PY - 2018 DA - 2018// TI - Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies JO - Microbiome. VL - 6 UR - https://doi.org/10.1186/s40168-018-0483-7 DO - 10.1186/s40168-018-0483-7 ID - Panebianco2018 ER - TY - JOUR AU - Wirbel, J. AU - Pyl, P. T. AU - Kartal, E. AU - Zych, K. AU - Kashani, A. AU - Milanese, A. PY - 2019 DA - 2019// TI - Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer JO - Nat Med VL - 25 UR - https://doi.org/10.1038/s41591-019-0406-6 DO - 10.1038/s41591-019-0406-6 ID - Wirbel2019 ER - TY - JOUR AU - Arthur, J. C. AU - Gharaibeh, R. Z. AU - Mühlbauer, M. AU - Perez-Chanona, E. AU - Uronis, J. M. AU - McCafferty, J. PY - 2014 DA - 2014// TI - Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer JO - Nat Commun VL - 5 UR - https://doi.org/10.1038/ncomms5724 DO - 10.1038/ncomms5724 ID - Arthur2014 ER - TY - STD TI - Allen J, Sears CL. Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development. Genome Med 2019;11(1):1–18. ID - ref24 ER - TY - JOUR AU - Yoon, H. AU - Kim, N. AU - Park, J. H. AU - Kim, Y. S. AU - Lee, J. AU - Kim, H. W. PY - 2017 DA - 2017// TI - Comparisons of gut microbiota among healthy control, patients with conventional adenoma, sessile serrated adenoma, and colorectal Cancer JO - J Cancer Prev VL - 22 UR - https://doi.org/10.15430/JCP.2017.22.2.108 DO - 10.15430/JCP.2017.22.2.108 ID - Yoon2017 ER - TY - JOUR AU - Peters, B. A. AU - Dominianni, C. AU - Shapiro, J. A. AU - Church, T. R. AU - Wu, J. AU - Miller, G. PY - 2016 DA - 2016// TI - The gut microbiota in conventional and serrated precursors of colorectal cancer JO - Microbiome. VL - 4 UR - https://doi.org/10.1186/s40168-016-0218-6 DO - 10.1186/s40168-016-0218-6 ID - Peters2016 ER - TY - JOUR AU - Park, C. H. AU - Han, D. S. AU - Oh, Y. H. AU - Lee, A. R. AU - Lee, Y. R. AU - Eun, C. S. PY - 2016 DA - 2016// TI - Role of Fusobacteria in the serrated pathway of colorectal carcinogenesis JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep25271 DO - 10.1038/srep25271 ID - Park2016 ER - TY - JOUR AU - Binda, E. AU - Visioli, A. AU - Giani, F. AU - Trivieri, N. AU - Palumbo, O. AU - Restelli, S. PY - 2017 DA - 2017// TI - Wnt5a drives an invasive phenotype in human Glioblastoma stem-like cells JO - Cancer Res VL - 77 UR - https://doi.org/10.1158/0008-5472.CAN-16-1693 DO - 10.1158/0008-5472.CAN-16-1693 ID - Binda2017 ER - TY - JOUR AU - Binda, E. AU - Visioli, A. AU - Giani, F. AU - Lamorte, G. AU - Copetti, M. AU - Pitter, K. L. PY - 2012 DA - 2012// TI - The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas JO - Cancer Cell VL - 22 UR - https://doi.org/10.1016/j.ccr.2012.11.005 DO - 10.1016/j.ccr.2012.11.005 ID - Binda2012 ER - TY - JOUR AU - Galli, R. AU - Binda, E. AU - Orfanelli, U. AU - Cipelletti, B. AU - Gritti, A. AU - Vitis, S. PY - 2004 DA - 2004// TI - Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma JO - Cancer Res VL - 64 UR - https://doi.org/10.1158/0008-5472.CAN-04-1364 DO - 10.1158/0008-5472.CAN-04-1364 ID - Galli2004 ER - TY - JOUR AU - Youden, W. J. PY - 1950 DA - 1950// TI - Index for rating diagnostic tests JO - Cancer. VL - 3 UR - https://doi.org/3.0.CO;2-3 DO - 3.0.CO;2-3 ID - Youden1950 ER - TY - JOUR AU - Wood, D. E. AU - Lu, J. AU - Langmead, B. PY - 2019 DA - 2019// TI - Improved metagenomic analysis with kraken 2 JO - Genome Biol VL - 20 UR - https://doi.org/10.1186/s13059-019-1891-0 DO - 10.1186/s13059-019-1891-0 ID - Wood2019 ER - TY - JOUR AU - Caporaso, J. G. AU - Kuczynski, J. AU - Stombaugh, J. AU - Bittinger, K. AU - Bushman, F. D. AU - Costello, E. K. PY - 2010 DA - 2010// TI - QIIME allows analysis of high-throughput community sequencing data JO - Nat Methods VL - 7 UR - https://doi.org/10.1038/nmeth.f.303 DO - 10.1038/nmeth.f.303 ID - Caporaso2010 ER - TY - JOUR AU - Langille, M. G. I. AU - Zaneveld, J. AU - Caporaso, J. G. AU - McDonald, D. AU - Knights, D. AU - Reyes, J. A. PY - 2013 DA - 2013// TI - Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences JO - Nat Biotechnol VL - 31 UR - https://doi.org/10.1038/nbt.2676 DO - 10.1038/nbt.2676 ID - Langille2013 ER - TY - JOUR AU - Parks, D. H. AU - Tyson, G. W. AU - Hugenholtz, P. AU - Beiko, R. G. PY - 2014 DA - 2014// TI - STAMP: statistical analysis of taxonomic and functional profiles JO - Bioinformatics. VL - 30 UR - https://doi.org/10.1093/bioinformatics/btu494 DO - 10.1093/bioinformatics/btu494 ID - Parks2014 ER - TY - JOUR AU - Pasolli, E. AU - Truong, D. T. AU - Malik, F. AU - Waldron, L. AU - Segata, N. PY - 2016 DA - 2016// TI - Machine learning meta-analysis of large metagenomic datasets: tools and biological insights JO - PLoS Comput Biol VL - 12 UR - https://doi.org/10.1371/journal.pcbi.1004977 DO - 10.1371/journal.pcbi.1004977 ID - Pasolli2016 ER - TY - JOUR AU - Jass, J. R. PY - 2007 DA - 2007// TI - Classification of colorectal cancer based on correlation of clinical, morphological and molecular features JO - Histopathology. VL - 50 UR - https://doi.org/10.1111/j.1365-2559.2006.02549.x DO - 10.1111/j.1365-2559.2006.02549.x ID - Jass2007 ER - TY - JOUR AU - Fessler, E. AU - Drost, J. AU - Hooff, S. R. AU - Linnekamp, J. F. AU - Wang, X. AU - Jansen, M. PY - 2016 DA - 2016// TI - TGFbeta signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype JO - EMBO Mol Med VL - 8 UR - https://doi.org/10.15252/emmm.201606184 DO - 10.15252/emmm.201606184 ID - Fessler2016 ER - TY - JOUR AU - Murakami, T. AU - Mitomi, H. AU - Saito, T. AU - Takahashi, M. AU - Sakamoto, N. AU - Fukui, N. PY - 2014 DA - 2014// TI - Distinct WNT/ β -catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum JO - Mod Pathol VL - 28 UR - https://doi.org/10.1038/modpathol.2014.41 DO - 10.1038/modpathol.2014.41 ID - Murakami2014 ER - TY - JOUR AU - Mori, G. AU - Rampelli, S. AU - Orena, B. S. AU - Rengucci, C. AU - Maio, G. D. AU - Barbieri, G. PY - 2018 DA - 2018// TI - Shifts of Faecal microbiota during sporadic colorectal carcinogenesis JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-017-17765-5 DO - 10.1038/s41598-017-17765-5 ID - Mori2018 ER - TY - JOUR AU - Zeller, G. AU - Tap, J. AU - Voigt, A. Y. AU - Sunagawa, S. AU - Kultima, J. R. AU - Costea, P. I. PY - 2014 DA - 2014// TI - Potential of fecal microbiota for early-stage detection of colorectal cancer JO - Mol Syst Biol VL - 10 UR - https://doi.org/10.15252/msb.20145645 DO - 10.15252/msb.20145645 ID - Zeller2014 ER - TY - JOUR AU - Liang, Q. AU - Ma, D. AU - Zhu, X. AU - Wang, Z. AU - Sun, T. T. AU - Shen, C. PY - 2018 DA - 2018// TI - RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 Ubiquitylation and associates with poor outcome in colorectal Cancer JO - Clin Cancer Res VL - 24 UR - https://doi.org/10.1158/1078-0432.CCR-17-2133 DO - 10.1158/1078-0432.CCR-17-2133 ID - Liang2018 ER - TY - JOUR AU - Ahn, J. AU - Sinha, R. AU - Pei, Z. AU - Dominianni, C. AU - Wu, J. AU - Shi, J. PY - 2013 DA - 2013// TI - Human gut microbiome and risk for colorectal cancer JO - J Natl Cancer Inst VL - 105 UR - https://doi.org/10.1093/jnci/djt300 DO - 10.1093/jnci/djt300 ID - Ahn2013 ER - TY - JOUR AU - Bhatt, A. P. AU - Redinbo, M. R. AU - Bultman, S. J. PY - 2017 DA - 2017// TI - The role of the microbiome in cancer development and therapy JO - CA Cancer J Clin VL - 67 UR - https://doi.org/10.3322/caac.21398 DO - 10.3322/caac.21398 ID - Bhatt2017 ER - TY - STD TI - Ryu SH, Kaiko GE, Stappenbeck TS. Cellular differentiation: Potential insight into butyrate paradox? Mol Cell Oncol. 52018. ID - ref45 ER - TY - JOUR AU - Canani, R. B. AU - Costanzo, M. D. AU - Leone, L. AU - Bedogni, G. AU - Brambilla, P. AU - Cianfarani, S. PY - 2011 DA - 2011// TI - Epigenetic mechanisms elicited by nutrition in early life JO - Nutr Res Rev VL - 24 UR - https://doi.org/10.1017/S0954422411000102 DO - 10.1017/S0954422411000102 ID - Canani2011 ER - TY - JOUR AU - Mangifesta, M. AU - Mancabelli, L. AU - Milani, C. AU - Gaiani, F. AU - Angelis, N. AU - Angelis, G. L. PY - 2018 DA - 2018// TI - Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-018-32413-2 DO - 10.1038/s41598-018-32413-2 ID - Mangifesta2018 ER - TY - JOUR AU - Gagnière, J. AU - Raisch, J. AU - Veziant, J. AU - Barnich, N. AU - Bonnet, R. AU - Buc, E. PY - 2016 DA - 2016// TI - Gut microbiota imbalance and colorectal cancer JO - World J Gastroenterol VL - 22 UR - https://doi.org/10.3748/wjg.v22.i2.501 DO - 10.3748/wjg.v22.i2.501 ID - Gagnière2016 ER - TY - JOUR AU - Ito, M. AU - Kanno, S. AU - Nosho, K. AU - Sukawa, Y. AU - Mitsuhashi, K. AU - Kurihara, H. PY - 2015 DA - 2015// TI - Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway JO - Int J Cancer VL - 137 UR - https://doi.org/10.1002/ijc.29488 DO - 10.1002/ijc.29488 ID - Ito2015 ER - TY - JOUR AU - Sideris, M. AU - Adams, K. AU - Moorhead, J. AU - Diaz-Cano, S. AU - Bjarnason, I. AU - Papagrigoriadis, S. PY - 2015 DA - 2015// TI - BRAF V600E mutation in colorectal cancer is associated with right-sided tumours and iron deficiency anaemia JO - Anticancer Res VL - 35 ID - Sideris2015 ER -