Fig. 3
Microbial communities associated to BRAFV600E and BRAF wt lesions. a Rarefaction curves for the analysis of microbial species content in the three groups of mice. b Microbial community a-diversity (top) and richness (middle and bottom) of the same groups at the genus (left) and species (right) level are shown. P values are from Kruskal-Wallis test are shown. c PCoA plot at the operational taxonomic unit (OTU) level showing the clustering pattern over time. d Ratio between Firmicutes and Bacteroidetes at 43DPT. **P < 0.01, one-way ANOVA Tukey’s multiple comparison test. Data are mean ± SEM. e Unsupervised hierarchical clustering analysis based on microbial communities’ presence at the family level showing an “healthy” profile in controls and a typical signature for each of the two CRC-carrier group. A dual-color code represents microbial families over-(red) and under-represented (blue)