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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: BRAFV600E mutation impinges on gut microbial markers defining novel biomarkers for serrated colorectal cancer effective therapies

Fig. 4

BRAFV600E CRC exhibits specific bacterial markers and a typical functional microbiota composition. Gut microbiota relative abundance (% similarity) at the phylum (a-b) and genus level (c-d) in gut microbiota of mice carrying BRAFV600E and BRAF wt CRC and controls at 7 DPT (a-c) and 43 DPT (b-d). e Significative relative abundance of predicted function (mean proportions %) and different abundance of predicted function (difference in mean proportion %) for specific KEGG modules level 2 in pairwise comparisons between controls, BRAFV600E (left; top) and BRAF wt CRCs (right) or between the two CRC groups (left; bottom). FDR-adjusted p value (q value) from Mann-Whitney test are shown

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