Fig. 1

Identification of MINPP1 by microarray and bioinformatics analyses. a A Volcano Plot was used to identify differentially expressed genes between HBV-positive and HBV-negative HCC tissues. b KEGG analysis of the down-regulated genes in HBV-positive and HBV-negative HCC tissues. c Heatmap clustering of down-regulated genes in HBV-positive and HBV-negative HCC. d Alluvial diagram represents genes involved in biological pathways. e RT-qPCR results of MINPP1 expression in 20 paired HBV-positive and HBV-negative HCC tissues. e The expression level of MINPP1 was verified in a HCC cohort from the TCGA database. ^*P < 0.05, ^**P < 0.01