Fig. 5From: Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axisMINPP1 and miRNA-30b-5p regulate glycolytic bypass metabolism of HBV-positive HCC cells. a Cellular glucose (left), lactate (middle), and 2--PG (right) levels in Hep3B cell carrying MINPP1 knockdown or overexpression. b Cellular glucose (left), lactate (middle), and 2--PG (right) level in Hep3B cells in which miRNA-30b-5p was inhibited or overexpressed. c The proliferation of Hep3B cells with MINPP1 knockdown and overexpression was determined under hypoxic and normoxic conditions with CCK-8 assays. *P < 0.05, **P < 0.01, ***P < 0.001Back to article page