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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness

Fig. 1

ANGPTL1 level was downregulated in CRC derived exosomes. a Transmission electron microscopy analysis of TDEs and NDEs. Scale bar, 100 nm. b The number of particles and median diameter was determined by dynamic light scattering (DLS) analysis. Data were shown as mean ± standard deviation of three technical replicates. c Western blot (WB) analysis of exosome biomarkers (Alix, TSG101, and CD9). d, e WB analysis of the ANGPTL1 in tissue-derived exosomes, n = 8, P = 0.03. ANGPTL1 level was downregulated in exosomes derived from CRC tumors than paired normal tissues. Data were analyzed using a ratio paired t-test

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