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Table 1 Relation between PD-1 epithelial TC cell expression and clinic-pathological features. * P < 0.05 among groups

From: PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells

 

Epithelial cell PD-1 staining

P

Negative/low

Positive

BRAF (n = 34)

 Not mutated

2

2

0.9

 Mutated

16

14

 

Thyroiditis (n = 33)

 No

12

11

0.9

 Yes

5

5

 

TNM (n = 34)

 T1

11

9

 

 T2

4

3

0.77

 T3

3

4

 

 N0

17

6

 

 N1

1

10

0.04*

 M0

11

15

 

 M1

7

1

0.9

Progression free survival (n = 28)

 No

3

4

 

 Yes

12

9

0.51

Stage (n = 29)

 1

12

6

 

 2

0

0

0.04*

 3

1

5

 

 4

2

3

 

Infiltrative phenotype (n = 34)

 No

15

13

 

 Yes

3

3

0.87