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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung cancer

Fig. 3

Lnc-GAN1 represses NSCLC cell growth in vivo. a The tumor masses are derived from H460 and A549 cells with overexpression of lnc-GAN1 or control vector, which were subcutaneously inoculated into the flank region of 6 nude mice, respectively. Upper penal: Negative controls; lower penal: lnc-GAN1 overexpression. b, c The weights (b) and volume (c) of the tumors derived from H460 and A549 cells with overexpression of Lnc-GAN1 or control vector, respectively. d Lnc-GAN1 extracted from  Xenotransplanted tumors was detected by qRT-PCR. e Ki-67 protein levels were detected with IHC in tumors derived from A549 or H460 cells with overexpressing lnc-GAN1 or control vector. *P < 0.05; ***P < 0.001

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