Fig. 4
From: A receptor-antibody hybrid hampering MET-driven metastatic spread
Receptor-antibody hybrid proteins inhibit pancreatic cancer cell dissemination in vivo. IVIS analysis of livers (A-B) or lungs (C-D) excised from hHGF-ki mice that received intra-pancreatic injections of Capan-1 or HPAF-II pancreatic cancer cells, respectively. Mice were treated with VEHICLE, the indicated hybrid proteins, or the combination of MvDN30 and decoyMETK842E (COMBO). Each dot represents the value of the organ excised from one mouse. The red line indicates the threshold (104) below which IVIS values are considered negative. **, p ≤ 0.01; *, p ≤ 0.05. Data reported in the figure are representative of one experiment out of two