Fig. 1

Expression of lincSCRG1 was strongly upregulated in both human tissues and cell lines of HCC. a Relative lincSCRG1, miR26a and SKP2 expression was detected by qPCR (each group n = 6) and the levels of SKP2 proteins were detected by western blot (each group n = 3) in human HCC tissues and adjacent liver tissues. b The expression of lincSCRG1was examined in different cell lines (hepatocyte cell line [LO2, AML12], primary hepatocyte [PHC] and HCC cell lines [HepG2, Hep3B, HCCLM3, SNU-387]) by qPCR. c The overexpression efficiency of ov-lincSCRG1 in Hep3B cells and the interference efficiency of sh-lincSCRG1 in SNU-387 cells were identified by qPCR. In (a), ^*indicates vs. the adjacent liver tissue group, p < 0.05; In (b)^*/**indicates vs. the LO2 group (^*, p < 0.05, ^**, p < 0.01); In (c-d) ^**indicatesvs. The NC group, p < 0.01, ^##indicatesvs. The ov-vector/sh-NC group, p < 0.01