Fig. 1

SBF2-AS1 and RRS1 are highly expressed, and miR-143 is poorly expressed in BC tissues and cell lines. a The expression of SBF2-AS1, miR-143 and RRS1 in BC tissues and adjacent normal tissues; b Protein band of RRS1 in BC tissues and adjacent normal tissues; c Statistical results of protein expression of RRS1; d The relation between SBF2-AS1 expression and miR-143 expression in BC patients was analyzed by Pearson correlation analysis; e The relation between SBF2-AS1 expression and RRS1 expression in BC patients was analyzed by Pearson correlation analysis; f Relation between miR-143 expression and RRS1 expression in BC patients was analyzed by Pearson correlation analysis. g The expression of SBF2-AS1, miR-143 and RRS1 in MCF-10A, MCF-7 and MDA-MB-231 cells; h Protein bands of RRS1 in MCF-10A, MCF-7 and MDA-MB-231 cells in Western blot analysis; i Statistical results of the protein expression of RRS1; j Expression of SBF2-AS1, miR-143 and RRS1 in MDA-MB-231 cells; k Protein band of RRS1 in MDA-MB-231 cells; l Protein expression of RRS1 in MDA-MB-231 cells; m Expression of SBF2-AS1, miR-143 and RRS1 in MCF-7 cells; n Protein band of RRS1 in MCF-7 cells; o Protein expression of RRS1 in MCF-7 cells. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. a–c: The t-test was performed for comparisons between two groups, n = 50, * P < 0.05 vs the adjacent normal tissues. g–o: One-way ANOVA was used for comparisons among multiple groups, and LSD-t test was used for pairwise comparisons after one-way ANOVA, N = 3, ^ P < 0.05 vs the MCF-10A cells; * P < 0.05 vs the si-NC group; # P < 0.05 vs the mimics NC group; & P < 0.05 vs the oe-SBF2-AS1 + mimics NC group