Fig. 5

Reduced SBF2-AS1 and overexpressed miR-143 accelerate cell cycle arrest and apoptosis of BC cells. a Apoptotic rate of MDA-MB-231 cells in each group was detected by flow cytometry; b Statistical results of the apoptotic rate of MDA-MB-231 cells in each group; c Apoptotic rate of MCF-7 cells in each group was detected by flow cytometry; d Statistical results of the apoptotic rate of MCF-7 cells in each group; e Cell cycle distribution of MDA-MB-231 cells was detected by flow cytometry; f Statistical results of MDA-MB-231 cell cycle distribution of each group; g Cell cycle distribution of MCF-7 cells was detected by flow cytometry; h Statistical results of MCF-7 cell cycle distribution of each group; i Protein bands of Bax and Bcl-2 in MDA-MB-231 cells in Western blot analysis; j Statistical results of the protein expression of Bax and Bcl-2 in MDA-MB-231 cells; k Protein bands of Bax and Bcl-2 in MCF-7 cells in Western blot analysis; l Statistical results of the protein expression of Bax and Bcl-2 in MCF-7 cells. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. One-way ANOVA was used for comparisons among multiple groups, and LSD-t test was used for pairwise comparisons after one-way ANOVA, N = 3, * P < 0.05 vs the si-NC group; # P < 0.05 vs the mimics NC group; & P < 0.05 vs the oe-SBF2-AS1 + mimics NC group