Fig. 6

Reduced SBF2-AS1 and overexpressed miR-143 restrain the invasion and migration of BC cells. a Invasion and migration abilities of MDA-MB-231 cells were detected by Transwell assay; b Statistical results of the number of migrated and invasive MDA-MB-231 cells; c Invasion and migration abilities of MCF-7 cells were detected by Transwell assay; d Statistical results of the number of migrated and invasive MCF-7 cells; e Protein bands of MMP-2 and MMP-9 in MDA-MB-231 cells in Western blot analysis; f Statistical results of the protein expression of MMP-2 and MMP-9 in MDA-MB-231 cells; g Protein bands of MMP-2 and MMP-9 in MCF-7 cells in Western blot analysis; h Statistical results of the protein expression of MMP-2 and MMP-9 in MCF-7 cells. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. One-way ANOVA was used for comparisons among multiple groups, and LSD-t test was used for pairwise comparisons after one-way ANOVA, N = 3, * P < 0.05 vs the si-NC group; # P < 0.05 vs the mimics NC group; & P < 0.05 vs the oe-SBF2-AS1 + mimics NC group