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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation

Fig. 2

KDM4B promotes the expression of GLUT1 via the AKT signaling pathway. a and b The phosphorylation of AKT at Thr 308 and Ser 473 and the expression of GLUT1 was detected in KDM4B-depressed(A)/overexpressed(B) CRC cells. c and d The expression of GLUT1 was detected in KDM4B-depressed LoVo/HCT116 cells transfected with myr-AKT. e and f The expression of GLUT1 was detected in KDM4B-overexpressed LoVo/HCT116 cells incubated with PI3K inhibitor LY294002

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