Fig. 2From: KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activationKDM4B promotes the expression of GLUT1 via the AKT signaling pathway. a and b The phosphorylation of AKT at Thr 308 and Ser 473 and the expression of GLUT1 was detected in KDM4B-depressed(A)/overexpressed(B) CRC cells. c and d The expression of GLUT1 was detected in KDM4B-depressed LoVo/HCT116 cells transfected with myr-AKT. e and f The expression of GLUT1 was detected in KDM4B-overexpressed LoVo/HCT116 cells incubated with PI3K inhibitor LY294002Back to article page