Fig. 1From: Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoidsEstablishment of HCC PDOs in vitro. a Workflow schematic. HCC specimens were obtained from patients who underwent surgery and processed as described in the Methods section to establish HCC PDOs. b Representative bright-field images of HCC PDOs from four individuals imaged with different magnification factors. Scale bar, 200 μmBack to article page