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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids

Fig. 6

Combined treatment with sorafenib and GANT61 significantly reduces HCC tumorigenesis in vivo. a (c) Photographs illustrating tumors in xenografts of BEL7402 or Hep3B cell lines under different treatments. b (d) The end tumor volume of BEL7402 or Hep3B cell lines under different treatment. e (f) Tumor growth of BEL7402 or Hep3B cell lines was monitored and shown under different treatments. g (h) Representative images showing H&E and immunofluorescence staining of Ki67 and TUNEL on tumors of different treatment are shown. Scale bar, 50 μm. (*p < 0.05, **p < 0.01, *** p < 0.001, **** p < 0.0001, P < 0.05 is considered statistically significant)

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