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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis

Fig. 1

The characteristics of Sora-resistant cells. (a) The IC50 of five HCC cell lines and LM3-SR cells to Sora were calculated using the CCK8 assay. (b) The colony forming ability of LM3 and LM3-SR cells (scale bar, 1 cm). (c) Hoechst 33342 staining used to show bright apoptotic cells. (d) Flow cytometry of cells stained with FITC and PI to determine apoptotic cells. The data is represented as mean ± SD. * indicates p < 0.05 vs. LM3-CTRL group. # indicates p < 0.05 vs. LM3-SR-CTRL group

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