Fig. 1
Characterization of exosomes derived from HCC cell lines. a TEM image of exosomes isolated from Hep3B and MHCC97H cell lines. b The size range of the exosomes isolated from Hep3B and MHCC97H cell lines checked by NAT analysis. c WB analysis of exosomal markers, including CD63, CD81 and CD9. d Hep3B cells co-cultured with exosomes derived from MHCC97H cells had higher invasive ability than that without MHCC97H exosomes treatment. e Histogram plot showed the number of invaded Hep3B cells with or without MHCC97H exosomes (represented by MHCC97H-exo) treatment. Significance was defined as P < .05 (*P < .05; ** P < .01; *** P < .001)