Fig. 4

Exosomal circRNA-100,338 regulates VM formation by regulating VE-cadherin. a The results showed that exosomes derived from circRNA-100,338 overexpressing Hep3B and knockdown MHCC97H significantly induced and reduced the protein levels of VE-Cadherin in HUEVC cells. b The results showed that exosomes derived from circRNA-100,338 overexpressing Hep3B (CIRC) and knockdown MHCC97H (siCIRC) significantly induced and reduced the protein levels of ZO-1 in HUEVC cells