Fig. 5

Overexpression of P53 promoted while inhibition of miR-200b blocked the effects of PinX1 overexpression on cell proliferation and sphere formation ability of nasopharyngeal CD133⁺ CSCs in vitro. a The cell viability curves of nasopharyngeal CD133⁺ CSCs following transfection as measured by CCK-8 assay. b Sphere formation ability of nasopharyngeal CD133⁺ CSCs following transfection in vitro as determined by colony formation analysis. * p < 0.05 vs. control