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Table 1 Summarization of the roles and functions of miR-210 in human cancers

From: The interplay between HIF-1α and noncoding RNAs in cancer

Role in cancer

Cancer types

Targets

Functions

References

oncogene

ovarian cancer

PTPN1

promotes proliferation, inhibits apoptosis

[33]

oncogene

hepatocellular cancer

AIFM3

promotes proliferation, inhibits apoptosis and radiosensitivity

[34]

oncogene

lung cancer

FGFRL1, E2F3, VMP1, RAD52, SDHD

promotes angiogenesis

[35]

oncogene

colon cancer

Bcl-2

enhances autophagy and reduces radiosensitivity

[36]

oncogene

breast cancer

N.A.

promotes proliferation, invasion and migration

[37]

oncogene

hepatocellular cancer

VMP1

promotes migration and invasion

[38]

oncogene

prostate cancer

TNIP1, SOCS1

promotes EMT, invasion and migration

[39]

oncogene

glioma

MNT

promotes hypoxic glioma stem cells stemness and radioresistance

[40]

oncogene

breast cancer

N.A.

N.A.

[41]

oncogene

renal cancer

ISCU1/2

N.A.

[42]

oncogene

gastric cancer

HOXA9

inhibits EMT, invasion and metastasis

[43]

oncogene

breast cancer

N.A.

promotes survival and invasion

[44]

tumor suppressor

esophageal cancer

FGFRL1

inhibits survival and proliferation

[45]

tumor suppressor

laryngocarcinoma

FGFRL1

inhibits proliferation

[46]

tumor suppressor

esophageal cancer

N.A.

promotes differentiation, inhibits radioresistance

[47]

tumor suppressor

renal cancer

ISCU

N.A.

[48]

tumor suppressor

renal cancer

E2F3

inhibits proliferation, induces multinucleation

[49]

tumor suppressor

neuroblastoma

Bcl-2

promotes apoptosis

[50]