From: The interplay between HIF-1α and noncoding RNAs in cancer
Role in cancer | Cancer types | Targets | Functions | References |
---|---|---|---|---|
oncogene | ovarian cancer | PTPN1 | promotes proliferation, inhibits apoptosis | [33] |
oncogene | hepatocellular cancer | AIFM3 | promotes proliferation, inhibits apoptosis and radiosensitivity | [34] |
oncogene | lung cancer | FGFRL1, E2F3, VMP1, RAD52, SDHD | promotes angiogenesis | [35] |
oncogene | colon cancer | Bcl-2 | enhances autophagy and reduces radiosensitivity | [36] |
oncogene | breast cancer | N.A. | promotes proliferation, invasion and migration | [37] |
oncogene | hepatocellular cancer | VMP1 | promotes migration and invasion | [38] |
oncogene | prostate cancer | TNIP1, SOCS1 | promotes EMT, invasion and migration | [39] |
oncogene | glioma | MNT | promotes hypoxic glioma stem cells stemness and radioresistance | [40] |
oncogene | breast cancer | N.A. | N.A. | [41] |
oncogene | renal cancer | ISCU1/2 | N.A. | [42] |
oncogene | gastric cancer | HOXA9 | inhibits EMT, invasion and metastasis | [43] |
oncogene | breast cancer | N.A. | promotes survival and invasion | [44] |
tumor suppressor | esophageal cancer | FGFRL1 | inhibits survival and proliferation | [45] |
tumor suppressor | laryngocarcinoma | FGFRL1 | inhibits proliferation | [46] |
tumor suppressor | esophageal cancer | N.A. | promotes differentiation, inhibits radioresistance | [47] |
tumor suppressor | renal cancer | ISCU | N.A. | [48] |
tumor suppressor | renal cancer | E2F3 | inhibits proliferation, induces multinucleation | [49] |
tumor suppressor | neuroblastoma | Bcl-2 | promotes apoptosis | [50] |