Fig. 3
From: Reversal of ABCB1-related multidrug resistance by ERK5-IN-1
Effect of ERK5-IN-1 on the intracellular accumulation of Dox. The intracellular accumulations of Dox in: a, KB and KBv200 cells; b, MCF7 and MCF7/adr cells; c, S1 and S1-MI-80 cells were measured by flow cytometric analysis, respectively. Right column presents the quantification of Dox fluorescence, which was calculated by dividing the fluorescence intensity of each sample with that of MDR cells. Data shown are means ± SD of triplicate determinations. **P < 0.01 significantly different from control group