TY - JOUR AU - Chan, H. C. S. AU - Li, Y. AU - Dahoun, T. AU - Vogel, H. AU - Yuan, S. PY - 2019 DA - 2019// TI - New binding sites, new opportunities for GPCR drug discovery JO - Trends Biochem Sci VL - 44 UR - https://doi.org/10.1016/j.tibs.2018.11.011 DO - 10.1016/j.tibs.2018.11.011 ID - Chan2019 ER - TY - JOUR AU - Insel, P. A. AU - Sriram, K. AU - Wiley, S. Z. AU - Wilderman, A. AU - Katakia, T. AU - McCann, T. PY - 2018 DA - 2018// TI - GPCRomics: GPCR expression in cancer cells and tumors identifies new, potential biomarkers and therapeutic targets JO - Front Pharmacol VL - 9 UR - https://doi.org/10.3389/fphar.2018.00431 DO - 10.3389/fphar.2018.00431 ID - Insel2018 ER - TY - JOUR AU - Enevoldsen, F. C. AU - Sahana, J. AU - Wehland, M. AU - Grimm, D. AU - Infanger, M. AU - Krüger, M. PY - 2020 DA - 2020// TI - Endothelin receptor antagonists: status quo and future perspectives for targeted therapy JO - J Clin Med VL - 9 UR - https://doi.org/10.3390/jcm9030824 DO - 10.3390/jcm9030824 ID - Enevoldsen2020 ER - TY - JOUR AU - Soond, S. M. AU - Zamyatnin, A. A. PY - 2020 DA - 2020// TI - Targeting G protein-coupled receptors in cancer therapy JO - Adv Cancer Res VL - 145 UR - https://doi.org/10.1016/bs.acr.2019.11.002 DO - 10.1016/bs.acr.2019.11.002 ID - Soond2020 ER - TY - JOUR AU - Rosanò, L. AU - Spinella, F. AU - Bagnato, A. PY - 2013 DA - 2013// TI - Endothelin 1 in cancer: biological implications and therapeutic opportunities JO - Nat Rev Cancer VL - 13 UR - https://doi.org/10.1038/nrc3546 DO - 10.1038/nrc3546 ID - Rosanò2013 ER - TY - JOUR AU - Gupta, S. AU - Prajapati, A. AU - Gulati, M. AU - Gautam, S. K. AU - Kumar, S. AU - Dalal, V. PY - 2020 DA - 2020// TI - Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer JO - Neoplasia VL - 22 UR - https://doi.org/10.1016/j.neo.2019.11.001 DO - 10.1016/j.neo.2019.11.001 ID - Gupta2020 ER - TY - JOUR AU - Thompson, M. D. AU - Cole, D. E. AU - Capra, V. AU - Siminovitch, K. A. AU - Rovati, G. E. AU - Burnham, W. M. PY - 2014 DA - 2014// TI - Pharmacogenetics of the G protein-coupled receptors JO - Methods Mol Biol VL - 1175 UR - https://doi.org/10.1007/978-1-4939-0956-8_9 DO - 10.1007/978-1-4939-0956-8_9 ID - Thompson2014 ER - TY - JOUR AU - Yanagisawa, M. AU - Kurihara, H. AU - Kimura, S. AU - Tomobe, Y. AU - Kobayashi, M. AU - Mitsui, Y. PY - 1988 DA - 1988// TI - A novel potent vasoconstrictor peptide produced by vascular endothelial cells JO - Nature VL - 332 UR - https://doi.org/10.1038/332411a0 DO - 10.1038/332411a0 ID - Yanagisawa1988 ER - TY - JOUR AU - Davenport, A. P. AU - Hyndman, K. A. AU - Dhaun, N. AU - Southan, C. AU - Kohan, D. E. AU - Pollock, J. S. PY - 2016 DA - 2016// JO - Endothelin Pharmacol Rev VL - 68 UR - https://doi.org/10.1124/pr.115.011833 DO - 10.1124/pr.115.011833 ID - Davenport2016 ER - TY - JOUR AU - Inoue, A. AU - Yanagisawa, M. AU - Kimura, S. AU - Kasuya, Y. AU - Miyauchi, T. AU - Goto, K. PY - 1989 DA - 1989// TI - The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes JO - Proc Natl Acad Sci USA VL - 86 UR - https://doi.org/10.1073/pnas.86.8.2863 DO - 10.1073/pnas.86.8.2863 ID - Inoue1989 ER - TY - JOUR AU - Arai, H. AU - Hori, S. AU - Aramori, I. AU - Ohkubo, H. AU - Nakanishi, S. PY - 1990 DA - 1990// TI - Cloning and expression of a cDNA encoding an endothelin receptor JO - Nature VL - 348 UR - https://doi.org/10.1038/348730a0 DO - 10.1038/348730a0 ID - Arai1990 ER - TY - JOUR AU - Rayhman, O. AU - Klipper, E. AU - Muller, L. AU - Davidson, B. AU - Reich, R. AU - Meidan, R. PY - 2008 DA - 2008// TI - Small interfering RNA molecules targeting endothelin-converting enzyme-1 inhibit endothelin-1 synthesis and the invasive phenotype of ovarian carcinoma cells JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-08-2093 DO - 10.1158/0008-5472.CAN-08-2093 ID - Rayhman2008 ER - TY - JOUR AU - Suleymanova, N. AU - Crudden, C. AU - Shibano, T. AU - Worrall, C. AU - Oprea, I. AU - Tica, A. PY - 2017 DA - 2017// TI - Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes JO - Oncogene VL - 36 UR - https://doi.org/10.1038/onc.2017.179 DO - 10.1038/onc.2017.179 ID - Suleymanova2017 ER - TY - JOUR AU - Luttrell, L. M. AU - Lefkowitz, R. J. PY - 2002 DA - 2002// TI - The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals JO - J Cell Sci VL - 115 UR - https://doi.org/10.1242/jcs.115.3.455 DO - 10.1242/jcs.115.3.455 ID - Luttrell2002 ER - TY - JOUR AU - Zhou, X. E. AU - Melcher, K. AU - Xu, H. E. PY - 2017 DA - 2017// TI - Understanding the GPCR biased signaling through G protein and arrestin complex structures JO - Curr Opin Struct Biol VL - 45 UR - https://doi.org/10.1016/j.sbi.2017.05.004 DO - 10.1016/j.sbi.2017.05.004 ID - Zhou2017 ER - TY - JOUR AU - Maguire, J. J. AU - Kuc, R. E. AU - Pell, V. R. AU - Green, A. AU - Brown, M. AU - Kumar, S. PY - 2012 DA - 2012// TI - Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways JO - Life Sci VL - 91 UR - https://doi.org/10.1016/j.lfs.2012.03.021 DO - 10.1016/j.lfs.2012.03.021 ID - Maguire2012 ER - TY - JOUR AU - Peterson, Y. K. AU - Luttrell, L. M. PY - 2017 DA - 2017// TI - The diverse roles of arrestin scaffolds in G-protein-coupled receptor signaling JO - Pharmacol Rev VL - 69 UR - https://doi.org/10.1124/pr.116.013367 DO - 10.1124/pr.116.013367 ID - Peterson2017 ER - TY - JOUR AU - Bremnes, T. AU - Paasche, J. D. AU - Mehlum, A. AU - Sandberg, C. AU - Bremnes, B. AU - Attramadal, H. PY - 2000 DA - 2000// TI - Regulation and intracellular trafficking pathways of the endothelin receptors JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M000142200 DO - 10.1074/jbc.M000142200 ID - Bremnes2000 ER - TY - JOUR AU - Shenoy, S. K. AU - McDonald, P. H. AU - Kohout, T. A. AU - Lefkowitz, R. J. PY - 2001 DA - 2001// TI - Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin JO - Science VL - 294 UR - https://doi.org/10.1126/science.1063866 DO - 10.1126/science.1063866 ID - Shenoy2001 ER - TY - JOUR AU - Rosanò, L. AU - Cianfrocca, R. AU - Masi, S. AU - Spinella, F. AU - Castro, V. AU - Biroccio, A. PY - 2009 DA - 2009// TI - Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis JO - Proc Natl Acad Sci U S A VL - 106 UR - https://doi.org/10.1073/pnas.0807158106 DO - 10.1073/pnas.0807158106 ID - Rosanò2009 ER - TY - JOUR AU - Cianfrocca, R. AU - Tocci, P. AU - Spinella, F. AU - Castro, V. AU - Bagnato, A. AU - Rosanò, L. PY - 2012 DA - 2012// TI - The endothelin A receptor and epidermal growth factor receptor signaling converge on β-catenin to promote ovarian cancer metastasis JO - Life Sci VL - 91 UR - https://doi.org/10.1016/j.lfs.2012.03.023 DO - 10.1016/j.lfs.2012.03.023 ID - Cianfrocca2012 ER - TY - JOUR AU - Bagnato, A. AU - Rosanò, L. PY - 2018 DA - 2018// TI - Endothelin-1 receptor drives invadopodia: exploiting how β-arrestin-1 guides the way JO - Small GTPases VL - 9 UR - https://doi.org/10.1080/21541248.2016.1235526 DO - 10.1080/21541248.2016.1235526 ID - Bagnato2018 ER - TY - JOUR AU - Semprucci, E. AU - Tocci, P. AU - Cianfrocca, R. AU - Sestito, R. AU - Caprara, V. AU - Veglione, M. PY - 2015 DA - 2015// TI - Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma JO - Oncogene VL - 35 UR - https://doi.org/10.1038/onc.2015.403 DO - 10.1038/onc.2015.403 ID - Semprucci2015 ER - TY - JOUR AU - Modugno, F. AU - Caprara, V. AU - Chellini, L. AU - Tocci, P. AU - Spadaro, F. AU - Ferrandina, G. PY - 2018 DA - 2018// TI - hMENA is a key regulator in endothelin-1/β-arrestin1-induced invadopodial function and metastatic process JO - Proc Natl Acad Sci USA VL - 115 UR - https://doi.org/10.1073/pnas.1715998115 DO - 10.1073/pnas.1715998115 ID - Modugno2018 ER - TY - JOUR AU - Chellini, L. AU - Caprara, V. AU - Spadaro, F. AU - Sestito, R. AU - Bagnato, A. AU - Rosanò, L. PY - 2018 DA - 2018// TI - Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signaling in ovarian cancer JO - Matrix Biol VL - 81 UR - https://doi.org/10.1016/j.matbio.2018.10.005 DO - 10.1016/j.matbio.2018.10.005 ID - Chellini2018 ER - TY - JOUR AU - Rosanò, L. AU - Cianfrocca, R. AU - Tocci, P. AU - Spinella, F. AU - Castro, V. AU - Spadaro, F. PY - 2013 DA - 2013// TI - β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling JO - Oncogene VL - 32 UR - https://doi.org/10.1038/onc.2012.527 DO - 10.1038/onc.2012.527 ID - Rosanò2013 ER - TY - JOUR AU - Cianfrocca, R. AU - Tocci, P. AU - Semprucci, E. AU - Spinella, F. AU - Castro, V. AU - Bagnato, A. PY - 2014 DA - 2014// TI - β-arrestin 1 is required for endothelin-1-induced NF-κB activation in ovarian cancer cells JO - Life Sci VL - 118 UR - https://doi.org/10.1016/j.lfs.2014.01.078 DO - 10.1016/j.lfs.2014.01.078 ID - Cianfrocca2014 ER - TY - JOUR AU - Cianfrocca, R. AU - Tocci, P. AU - Rosanò, L. AU - Caprara, V. AU - Sestito, R. AU - Castro, V. PY - 2016 DA - 2016// TI - Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression JO - Oncotarget VL - 7 UR - https://doi.org/10.18632/oncotarget.7461 DO - 10.18632/oncotarget.7461 ID - Cianfrocca2016 ER - TY - JOUR AU - Shenoy, S. K. AU - Han, S. AU - Zhao, Y. L. AU - Hara, M. R. AU - Oliver, T. AU - Cao, Y. PY - 2012 DA - 2012// TI - β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression JO - Oncogene VL - 31 UR - https://doi.org/10.1038/onc.2011.238 DO - 10.1038/onc.2011.238 ID - Shenoy2012 ER - TY - JOUR AU - Perumal, D. AU - Smitha, P. AU - Nguyen, J. AU - Schaal, C. AU - Coppola, D. AU - Chellappan, S. P. PY - 2014 DA - 2014// TI - Nicotinic acetylcholine receptors induce c-Kit ligand/stem cell factor and promote stemness in an ARRB1/β-arrestin-1 dependent manner in NSCLC JO - Oncotarget VL - 5 UR - https://doi.org/10.18632/oncotarget.2395 DO - 10.18632/oncotarget.2395 ID - Perumal2014 ER - TY - JOUR AU - Zecchini, V. AU - Madhu, B. AU - Russell, R. AU - Pértega-Gomes, N. AU - Warren, A. AU - Gaude, E. PY - 2014 DA - 2014// TI - Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer JO - EMBO J VL - 33 UR - https://doi.org/10.15252/embj.201386874 DO - 10.15252/embj.201386874 ID - Zecchini2014 ER - TY - JOUR AU - Pillai, S. AU - Trevino, J. AU - Rawal, B. AU - Singh, S. AU - Kovacs, M. AU - Li, X. PY - 2015 DA - 2015// TI - β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition JO - Cancer Res VL - 75 UR - https://doi.org/10.1158/0008-5472.CAN-14-0681 DO - 10.1158/0008-5472.CAN-14-0681 ID - Pillai2015 ER - TY - JOUR AU - Rosanò, L. AU - Cianfrocca, R. AU - Tocci, P. AU - Spinella, F. AU - Castro, V. AU - Caprara, V. PY - 2014 DA - 2014// TI - Endothelin A receptor/β-arrestin signalling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-3133 DO - 10.1158/0008-5472.CAN-13-3133 ID - Rosanò2014 ER - TY - JOUR AU - Cianfrocca, R. AU - Rosanò, L. AU - Tocci, P. AU - Sestito, R. AU - Caprara, V. AU - Castro, V. PY - 2017 DA - 2017// TI - Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancer JO - Cell Death Differ VL - 24 UR - https://doi.org/10.1038/cdd.2017.121 DO - 10.1038/cdd.2017.121 ID - Cianfrocca2017 ER - TY - JOUR AU - Rosanò, L. AU - Bagnato, A. PY - 2016 DA - 2016// TI - β-arrestin1 at the cross-road of endothelin-1 signaling in cancer JO - J Exp Clin Cancer Res VL - 35 UR - https://doi.org/10.1186/s13046-016-0401-4 DO - 10.1186/s13046-016-0401-4 ID - Rosanò2016 ER - TY - STD TI - Böttke T, Ernicke S, Serfling R, Ihling C, Burda E, Gurevich VV, et al. Exploring GPCR-arrestin interfaces with genetically encoded crosslinkers. EMBO Rep. 2020;e50437. ID - ref36 ER - TY - JOUR AU - Vacca, F. AU - Bagnato, A. AU - Catt, K. J. AU - Tecce, R. PY - 2000 DA - 2000// TI - Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells JO - Cancer Res VL - 60 ID - Vacca2000 ER - TY - JOUR AU - Zhang, Y. AU - Li, M. AU - Li, L. AU - Qian, G. AU - Wang, Y. AU - Chen, Z. PY - 2020 DA - 2020// TI - β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion JO - Nat Commun VL - 11 UR - https://doi.org/10.1038/s41467-020-19849-9 DO - 10.1038/s41467-020-19849-9 ID - Zhang2020 ER - TY - JOUR AU - Moody, T. W. AU - Ramos-Alvarez, I. AU - Moreno, P. AU - Mantey, S. A. AU - Ridnour, L. PY - 2017 DA - 2017// TI - Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells JO - Peptides VL - 90 UR - https://doi.org/10.1016/j.peptides.2017.01.012 DO - 10.1016/j.peptides.2017.01.012 ID - Moody2017 ER - TY - JOUR AU - Crudden, C. AU - Shibano, T. AU - Song, D. AU - Suleymanova, N. AU - Girnita, A. AU - Girnita, L. PY - 2018 DA - 2018// TI - Blurring boundaries: receptor tyrosine kinases as functional G protein-coupled receptors JO - Int Rev Cell Mol Biol VL - 339 UR - https://doi.org/10.1016/bs.ircmb.2018.02.006 DO - 10.1016/bs.ircmb.2018.02.006 ID - Crudden2018 ER - TY - JOUR AU - Usui, I. AU - Imamura, T. AU - Huang, J. AU - Satoh, H. AU - Shenoy, S. K. AU - Lefkowitz, R. J. PY - 2004 DA - 2004// TI - Beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1 JO - Mol Cell Biol VL - 24 UR - https://doi.org/10.1128/MCB.24.20.8929-8937.2004 DO - 10.1128/MCB.24.20.8929-8937.2004 ID - Usui2004 ER - TY - JOUR AU - Lee, J. AU - Banu, S. K. AU - Burghardt, R. C. AU - Starzinski-Powitz, A. AU - Arosh, J. A. PY - 2013 DA - 2013// TI - Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through suppression of integrin-mediated mechanisms JO - Biol Reprod VL - 88 UR - https://doi.org/10.1095/biolreprod.112.100883 DO - 10.1095/biolreprod.112.100883 ID - Lee2013 ER - TY - JOUR AU - Boularan, C. AU - Scott, M. G. AU - Bourougaa, K. AU - Bellal, M. AU - Esteve, E. AU - Thuret, A. PY - 2007 DA - 2007// TI - beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53 JO - Proc Natl Acad Sci U S A VL - 104 UR - https://doi.org/10.1073/pnas.0705550104 DO - 10.1073/pnas.0705550104 ID - Boularan2007 ER - TY - JOUR AU - Bagnato, A. AU - Rosanò, L. PY - 2019 DA - 2019// TI - New routes in GPCR/β-arrestin-driven signaling in cancer progression and metastasis JO - Front Pharmacol VL - 10 UR - https://doi.org/10.3389/fphar.2019.00114 DO - 10.3389/fphar.2019.00114 ID - Bagnato2019 ER - TY - JOUR AU - Rosanò, L. AU - Cianfrocca, R. AU - Spinella, F. AU - Castro, V. AU - Nicotra, M. R. AU - Lucidi, A. PY - 2011 DA - 2011// TI - Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells JO - Clin Cancer Res VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-10-2325 DO - 10.1158/1078-0432.CCR-10-2325 ID - Rosanò2011 ER - TY - JOUR AU - Ahn, H. M. AU - Kim, D. G. AU - Kim, Y. J. PY - 2020 DA - 2020// TI - Blockade of endothelin receptor A enhances the therapeutic efficacy of gemcitabine in pancreatic cancer cells JO - Biochem Biophys Res Commun VL - 527 UR - https://doi.org/10.1016/j.bbrc.2020.04.118 DO - 10.1016/j.bbrc.2020.04.118 ID - Ahn2020 ER - TY - JOUR AU - Zhao, Y. AU - Liao, Q. AU - Zhu, Y. AU - Long, H. PY - 2011 DA - 2011// TI - Endothelin-1 promotes osteosarcoma cell invasion and survival against cisplatin-induced apoptosis JO - Clin Orthop Relat Res VL - 469 UR - https://doi.org/10.1007/s11999-011-1939-2 DO - 10.1007/s11999-011-1939-2 ID - Zhao2011 ER - TY - JOUR AU - Mai, H. Q. AU - Zeng, Z. Y. AU - Feng, K. T. AU - Ye, Y. L. AU - Zhang, C. Q. AU - Liang, W. J. PY - 2006 DA - 2006// TI - Therapeutic targeting of the endothelin A receptor in human nasopharyngeal carcinoma JO - Cancer Sci VL - 97 UR - https://doi.org/10.1111/j.1349-7006.2006.00333.x DO - 10.1111/j.1349-7006.2006.00333.x ID - Mai2006 ER - TY - JOUR AU - Banerjee, S. AU - Hussain, M. AU - Wang, Z. AU - Saliganan, A. AU - Che, M. AU - Bonfil, D. PY - 2007 DA - 2007// TI - In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer JO - Cancer Res. VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-06-3879 DO - 10.1158/0008-5472.CAN-06-3879 ID - Banerjee2007 ER - TY - JOUR AU - Rosanò, L. AU - Castro, V. AU - Spinella, F. AU - Nicotra, M. R. AU - Natali, P. G. AU - Bagnato, A. PY - 2007 DA - 2007// TI - ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-07-0151 DO - 10.1158/1535-7163.MCT-07-0151 ID - Rosanò2007 ER - TY - JOUR AU - Papanikolaou, S. AU - Bravou, V. AU - Papadaki, H. AU - Gyftopoulos, K. PY - 2017 DA - 2017// TI - The role of the endothelin axis in promoting epithelial to mesenchymal transition and lymph node metastasis in prostate adenocarcinoma JO - Urol Ann VL - 9 UR - https://doi.org/10.4103/UA.UA_43_17 DO - 10.4103/UA.UA_43_17 ID - Papanikolaou2017 ER - TY - JOUR AU - Shibue, T. AU - Weinberg, R. A. PY - 2017 DA - 2017// TI - EMT, CSCs, and drug resistance: the mechanistic link and clinical implications JO - Nat Rev Clin Oncol VL - 14 UR - https://doi.org/10.1038/nrclinonc.2017.44 DO - 10.1038/nrclinonc.2017.44 ID - Shibue2017 ER - TY - JOUR AU - Yuan, W. AU - Qian, M. AU - Li, Z. X. AU - Zhao, C. L. AU - Zhao, J. AU - Xiao, J. R. PY - 2019 DA - 2019// TI - Endothelin-1 activates the Notch signaling pathway and promotes tumorigenesis in giant cell tumor of the spine JO - Spine VL - 44 UR - https://doi.org/10.1097/BRS.0000000000003044 DO - 10.1097/BRS.0000000000003044 ID - Yuan2019 ER - TY - JOUR AU - Ma, Z. AU - Yu, Y. R. AU - Badea, C. T. AU - Kovacs, J. J. AU - Xiong, X. AU - Comhairet, S. PY - 2019 DA - 2019// TI - Vascular endothelial growth factor receptor 3 regulates endothelial function through β-arrestin 1 JO - Circulation VL - 139 UR - https://doi.org/10.1161/CIRCULATIONAHA.118.034961 DO - 10.1161/CIRCULATIONAHA.118.034961 ID - Ma2019 ER - TY - JOUR AU - Kedziora, K. M. AU - Leyton-Puig, D. AU - Argenzio, E. AU - Boumeester, A. J. AU - Butselaar, B. AU - Yinet, T. PY - 2016 DA - 2016// TI - Rapid remodeling of invadosomes by Gi-coupled receptors: dissecting the role of Rho GTPases JO - J Biol Chem VL - 291 UR - https://doi.org/10.1074/jbc.M115.695940 DO - 10.1074/jbc.M115.695940 ID - Kedziora2016 ER - TY - JOUR AU - Salani, D. AU - Taraboletti, G. AU - Rosanò, L. AU - Castro, V. AU - Borsotti, P. AU - Giavazzi, R. PY - 2000 DA - 2000// TI - Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo JO - Am J Pathol VL - 157 UR - https://doi.org/10.1016/S0002-9440(10)64807-9 DO - 10.1016/S0002-9440(10)64807-9 ID - Salani2000 ER - TY - JOUR AU - Spinella, F. AU - Garrafa, E. AU - Castro, V. AU - Rosanò, L. AU - Nicotra, M. R. AU - Caruso, A. PY - 2009 DA - 2009// TI - Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade JO - Cancer Res VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-08-1879 DO - 10.1158/0008-5472.CAN-08-1879 ID - Spinella2009 ER - TY - JOUR AU - Morand, J. AU - Briançon-Marjollet, A. AU - Lemarie, E. AU - Gonthier, B. AU - Arnaud, J. AU - Korichnevaet, I. PY - 2019 DA - 2019// TI - Zinc deficiency promotes endothelin secretion and endothelial cell migration through nuclear hypoxia-inducible factor-1 translocation JO - Am J Physiol Cell Physiol VL - 317 UR - https://doi.org/10.1152/ajpcell.00460.2018 DO - 10.1152/ajpcell.00460.2018 ID - Morand2019 ER - TY - JOUR AU - Spinella, F. AU - Caprara, V. AU - Cianfrocca, R. AU - Rosanò, L. AU - Castro, V. AU - Garrafa, E. PY - 2014 DA - 2014// TI - The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor JO - Carcinogenesis VL - 35 UR - https://doi.org/10.1093/carcin/bgu018 DO - 10.1093/carcin/bgu018 ID - Spinella2014 ER - TY - JOUR AU - Knowles, J. P. AU - Shi-Wen, X. AU - Haque, S. AU - Bhalla, A. AU - Dashwood, M. R. AU - Yang, S. PY - 2012 DA - 2012// TI - Endothelin-1 stimulates colon cancer adjacent fibroblasts JO - Int J Cancer VL - 130 UR - https://doi.org/10.1002/ijc.26090 DO - 10.1002/ijc.26090 ID - Knowles2012 ER - TY - JOUR AU - Moraitis, S. AU - Miller, W. R. AU - Smyth, J. F. AU - Langdon, S. P. PY - 1999 DA - 1999// TI - Paracrine regulation of ovarian cancer by endothelin JO - Eur J Cancer VL - 35 UR - https://doi.org/10.1016/S0959-8049(99)00131-8 DO - 10.1016/S0959-8049(99)00131-8 ID - Moraitis1999 ER - TY - JOUR AU - Schrey, M. P. AU - Patel, K. V. AU - Tezapsidis, N. PY - 1992 DA - 1992// TI - Bombesin and glucocorticoids stimulate human breast cancer cells to produce endothelin, a paracrine mitogen for breast stromal cells JO - Cancer Res VL - 52 ID - Schrey1992 ER - TY - JOUR AU - Patel, K. V. AU - Sheth, H. G. AU - Schrey, M. P. PY - 1997 DA - 1997// TI - Stimulation or endothelin–1 secretion by human breast cancer cells through protein kinase A activation: a possible novel paracrine loop involving breast fibroblast-derived prostaglandin E2 JO - Mol Cell Endocrinol VL - 126 UR - https://doi.org/10.1016/S0303-7207(96)03983-4 DO - 10.1016/S0303-7207(96)03983-4 ID - Patel1997 ER - TY - JOUR AU - Guruli, G. AU - Pflug, B. R. AU - Pecher, S. AU - Makarenkova, V. AU - Shurin, M. R. AU - Nelson, J. B. PY - 2004 DA - 2004// TI - Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops JO - Blood VL - 104 UR - https://doi.org/10.1182/blood-2003-10-3559 DO - 10.1182/blood-2003-10-3559 ID - Guruli2004 ER - TY - JOUR AU - Kandalaft, L. E. AU - Motz, G. T. AU - Duraiswamy, J. AU - Coukos, G. PY - 2011 DA - 2011// TI - Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance JO - Cancer Metastasis Rev VL - 30 UR - https://doi.org/10.1007/s10555-011-9289-9 DO - 10.1007/s10555-011-9289-9 ID - Kandalaft2011 ER - TY - JOUR AU - Kandalaft, L. E. AU - Facciabene, A. AU - Buckanovich, R. J. AU - Coukos, G. PY - 2009 DA - 2009// TI - Endothelin B receptor, a new target in cancer immune therapy JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-0543 DO - 10.1158/1078-0432.CCR-08-0543 ID - Kandalaft2009 ER - TY - JOUR AU - Hinsley, E. E. AU - Kumar, S. AU - Hunter, K. D. AU - Whawell, S. A. AU - Lambert, D. W. PY - 2012 DA - 2012// TI - Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion JO - Life Sci VL - 91 UR - https://doi.org/10.1016/j.lfs.2012.04.001 DO - 10.1016/j.lfs.2012.04.001 ID - Hinsley2012 ER - TY - JOUR AU - Buckanovich, R. J. AU - Facciabene, A. AU - Kim, S. AU - Benencia, F. AU - Sasaroli, D. AU - Balint, K. PY - 2008 DA - 2008// TI - Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy JO - Nat Med VL - 14 UR - https://doi.org/10.1038/nm1699 DO - 10.1038/nm1699 ID - Buckanovich2008 ER - TY - JOUR AU - Yu, F. X. AU - Zhao, B. AU - Panupinthu, N. AU - Jewell, J. L. AU - Lian, I. AU - Wang, L. H. PY - 2012 DA - 2012// TI - Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling JO - Cell VL - 150 UR - https://doi.org/10.1016/j.cell.2012.06.037 DO - 10.1016/j.cell.2012.06.037 ID - Yu2012 ER - TY - JOUR AU - Totaro, A. AU - Panciera, T. AU - Piccolo, S. PY - 2018 DA - 2018// TI - YAP/TAZ upstream signals and downstream responses JO - Nat Cell Biol VL - 20 UR - https://doi.org/10.1038/s41556-018-0142-z DO - 10.1038/s41556-018-0142-z ID - Totaro2018 ER - TY - JOUR AU - Zanconato, F. AU - Cordenonsi, M. AU - Piccolo, S. PY - 2019 DA - 2019// TI - YAP and TAZ: a signalling hub of the tumour microenvironment JO - Nat Rev Cancer VL - 19 UR - https://doi.org/10.1038/s41568-019-0168-y DO - 10.1038/s41568-019-0168-y ID - Zanconato2019 ER - TY - JOUR AU - Cai, H. AU - Xu, Y. PY - 2013 DA - 2013// TI - The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells JO - Cell Commun Signal VL - 11 UR - https://doi.org/10.1186/1478-811X-11-31 DO - 10.1186/1478-811X-11-31 ID - Cai2013 ER - TY - JOUR AU - Cheng, J. C. AU - Wang, E. Y. AU - Yi, Y. AU - Thakur, A. AU - Tsai, S. H. AU - Hoodless, P. A. PY - 2018 DA - 2018// TI - S1P stimulates proliferation by upregulating CTGF expression through S1PR2-mediated YAP activation JO - Mol Cancer Res VL - 16 UR - https://doi.org/10.1158/1541-7786.MCR-17-0681 DO - 10.1158/1541-7786.MCR-17-0681 ID - Cheng2018 ER - TY - JOUR AU - Zhou, X. AU - Wang, S. AU - Wang, Z. AU - Feng, X. AU - Liu, P. AU - Lv, X. -. B. PY - 2015 DA - 2015// TI - Estrogen regulates Hippo signaling via GPER in breast cancer JO - J Clin Invest VL - 125 UR - https://doi.org/10.1172/JCI79573 DO - 10.1172/JCI79573 ID - Zhou2015 ER - TY - JOUR AU - Mo, J. S. AU - Yu, F. X. AU - Gong, R. AU - Brown, J. H. AU - Guan, K. L. PY - 2012 DA - 2012// TI - Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs) JO - Genes Dev VL - 26 UR - https://doi.org/10.1101/gad.197582.112 DO - 10.1101/gad.197582.112 ID - Mo2012 ER - TY - JOUR AU - Nag, J. K. AU - Bar-Shavit, R. PY - 2018 DA - 2018// TI - Transcriptional landscape of PARs in epithelial malignancies JO - Int J Mol Sci VL - 19 UR - https://doi.org/10.3390/ijms19113451 DO - 10.3390/ijms19113451 ID - Nag2018 ER - TY - JOUR AU - Saikawa, S. AU - Kaji, K. AU - Nishimura, N. AU - Seki, K. AU - Sato, S. AU - Nakanishi, K. PY - 2018 DA - 2018// TI - Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein JO - Cancer Lett VL - 434 UR - https://doi.org/10.1016/j.canlet.2018.07.021 DO - 10.1016/j.canlet.2018.07.021 ID - Saikawa2018 ER - TY - JOUR AU - Uemura, H. AU - Hasumi, H. AU - Ishiguro, H. AU - Teranishi, J. AU - Miyoshi, Y. AU - Kubota, Y. PY - 2006 DA - 2006// TI - Renin-angiotensin system is an important factor in hormone refractory prostate cancer JO - Prostate VL - 66 UR - https://doi.org/10.1002/pros.20407 DO - 10.1002/pros.20407 ID - Uemura2006 ER - TY - JOUR AU - Kim, H. B. AU - Kim, M. AU - Park, Y. S. AU - Park, I. AU - Kim, T. AU - Yang, S. Y. PY - 2017 DA - 2017// TI - Prostaglandin E2 activates YAP and a positive-signaling loop to promote colon regeneration after colitis but also carcinogenesis in Mice JO - Gastroenterology VL - 152 UR - https://doi.org/10.1053/j.gastro.2016.11.005 DO - 10.1053/j.gastro.2016.11.005 ID - Kim2017 ER - TY - JOUR AU - Xu, G. AU - Wang, Y. AU - Li, W. AU - Cao, Y. AU - Xu, J. AU - Hu, Z. PY - 2018 DA - 2018// TI - COX-2 forms regulatory loop with YAP to promote proliferation and tumorigenesis of hepatocellular carcinoma cells JO - Neoplasia VL - 20 UR - https://doi.org/10.1016/j.neo.2017.12.004 DO - 10.1016/j.neo.2017.12.004 ID - Xu2018 ER - TY - JOUR AU - Zheng, C. H. AU - Chen, X. M. AU - Zhang, F. B. AU - Zhao, C. AU - Tu, S. S. PY - 2018 DA - 2018// TI - Inhibition of CXCR4 regulates epithelial mesenchymal transition of NSCLC via the Hippo-YAP signaling pathway JO - Cell Biol Int VL - 42 UR - https://doi.org/10.1002/cbin.11024 DO - 10.1002/cbin.11024 ID - Zheng2018 ER - TY - JOUR AU - Wang, J. AU - Hong, Y. AU - Shao, S. AU - Zhang, K. AU - Hong, W. PY - 2018 DA - 2018// TI - FFAR1-and FFAR4-dependent activation of Hippo pathway mediates DHA-induced apoptosis of androgen-independent prostate cancer cells JO - Biochem Biophys Res Commun VL - 506 UR - https://doi.org/10.1016/j.bbrc.2018.10.088 DO - 10.1016/j.bbrc.2018.10.088 ID - Wang2018 ER - TY - JOUR AU - Park, H. W. AU - Kim, Y. C. AU - Yu, B. AU - Moroishi, T. AU - Mo, J. -. S. AU - Plouffe, S. W. PY - 2015 DA - 2015// TI - Alternative Wnt signaling activates YAP/TAZ JO - Cell VL - 162 UR - https://doi.org/10.1016/j.cell.2015.07.013 DO - 10.1016/j.cell.2015.07.013 ID - Park2015 ER - TY - JOUR AU - Luo, J. AU - Yu, F. X. PY - 2019 DA - 2019// TI - GPCR-Hippo signaling in cancer JO - Cells VL - 8 UR - https://doi.org/10.3390/cells8050426 DO - 10.3390/cells8050426 ID - Luo2019 ER - TY - JOUR AU - Nieto Gutierrez, A. AU - McDonald, P. H. AU - GPCRs PY - 2018 DA - 2018// TI - Emerging anti-cancer drug targets JO - Cell Signal VL - 41 UR - https://doi.org/10.1016/j.cellsig.2017.09.005 DO - 10.1016/j.cellsig.2017.09.005 ID - Nieto Gutierrez2018 ER - TY - JOUR AU - Park, H. W. AU - Guan, K. L. PY - 2013 DA - 2013// TI - Regulation of the Hippo pathway and implications for anticancer drug development JO - Trends Pharmacol Sci VL - 34 UR - https://doi.org/10.1016/j.tips.2013.08.006 DO - 10.1016/j.tips.2013.08.006 ID - Park2013 ER - TY - JOUR AU - Wang, Z. AU - Liu, P. AU - Zhou, X. AU - Wang, T. AU - Feng, X. AU - Sunet, Y. -. P. PY - 2017 DA - 2017// TI - Endothelin promotes colorectal tumorigenesis by activating YAP/TAZ JO - Cancer Res VL - 77 UR - https://doi.org/10.1158/0008-5472.CAN-16-3229 DO - 10.1158/0008-5472.CAN-16-3229 ID - Wang2017 ER - TY - JOUR AU - Tocci, P. AU - Cianfrocca, R. AU - Castro, V. AU - Rosanò, L. AU - Sacconi, A. AU - Donzelli, S. PY - 2019 DA - 2019// TI - β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer JO - Nat Commun VL - 10 UR - https://doi.org/10.1038/s41467-019-11045-8 DO - 10.1038/s41467-019-11045-8 ID - Tocci2019 ER - TY - JOUR AU - Tocci, P. AU - Cianfrocca, R. AU - Sestito, R. AU - Rosanò, L. AU - Castro, V. AU - Blandino, G. PY - 2020 DA - 2020// TI - Endothelin-1 axis fosters YAP-induced chemotherapy escape in ovarian cancer JO - Cancer Lett VL - 492 UR - https://doi.org/10.1016/j.canlet.2020.08.026 DO - 10.1016/j.canlet.2020.08.026 ID - Tocci2020 ER - TY - JOUR AU - Shreberk-Shaked, M. AU - Dassa, B. AU - Sinha, S. AU - Agostino, S. AU - Azuri, I. AU - Mukherjee, S. PY - 2020 DA - 2020// TI - A Division of labor between YAP and TAZ in non-small cell lung cancer JO - Cancer Res VL - 80 UR - https://doi.org/10.1158/0008-5472.CAN-20-0125 DO - 10.1158/0008-5472.CAN-20-0125 ID - Shreberk-Shaked2020 ER - TY - JOUR AU - Clines, G. A. AU - Mohammad, K. S. AU - Bao, Y. AU - Stephens, O. W. AU - Suva, L. J. AU - Shaughnessy, F. D. PY - 2007 DA - 2007// TI - Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation JO - Mol Endocrinol VL - 21 UR - https://doi.org/10.1210/me.2006-0346 DO - 10.1210/me.2006-0346 ID - Clines2007 ER - TY - JOUR AU - Rodriguez-Vita, J. AU - Ruiz-Ortega, M. AU - Rupérez, M. AU - Esteban, V. AU - Sanchez-López, E. AU - Plaza, J. J. PY - 2005 DA - 2005// TI - Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells JO - Circ Res VL - 97 UR - https://doi.org/10.1161/01.RES.0000174614.74469.83 DO - 10.1161/01.RES.0000174614.74469.83 ID - Rodriguez-Vita2005 ER - TY - JOUR AU - Recchia, A. G. AU - Filice, E. AU - Pellegrino, D. AU - Dobrina, A. AU - Cerra, M. C. AU - Maggiolini, M. PY - 2009 DA - 2009// TI - Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes JO - J Mol Cell Cardiol VL - 46 UR - https://doi.org/10.1016/j.yjmcc.2008.11.017 DO - 10.1016/j.yjmcc.2008.11.017 ID - Recchia2009 ER - TY - JOUR AU - Weng, C. M. AU - Yu, C. C. AU - Kuo, M. L. AU - Chen, B. C. AU - Lin, C. H. PY - 2014 DA - 2014// TI - Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by ETAR-dependent JNK/AP-1 pathway JO - Biochem Pharmacol VL - 88 UR - https://doi.org/10.1016/j.bcp.2014.01.030 DO - 10.1016/j.bcp.2014.01.030 ID - Weng2014 ER - TY - JOUR AU - Faião-Flores, F. AU - Emmons, M. F. AU - Durante, M. A. AU - Kinose, F. AU - Saha, B. AU - Fang, B. PY - 2019 DA - 2019// TI - HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma JO - Clin Cancer Res VL - 25 UR - https://doi.org/10.1158/1078-0432.CCR-18-3382 DO - 10.1158/1078-0432.CCR-18-3382 ID - Faião-Flores2019 ER - TY - JOUR AU - Zhao, B. AU - Ye, X. AU - Yu, J. AU - Li, L. AU - Li, W. AU - Li, S. PY - 2008 DA - 2008// TI - TEAD mediates YAP-dependent gene induction and growth control JO - Genes Dev VL - 22 UR - https://doi.org/10.1101/gad.1664408 DO - 10.1101/gad.1664408 ID - Zhao2008 ER - TY - JOUR AU - Tocci, P. AU - Rosanò, L. AU - Bagnato, A. PY - 2019 DA - 2019// TI - Targeting endothelin-1 receptor/β-arrestin-1 axis in ovarian cancer: from basic research to a therapeutic approach JO - Front Endocrinol VL - 10 UR - https://doi.org/10.3389/fendo.2019.00609 DO - 10.3389/fendo.2019.00609 ID - Tocci2019 ER - TY - JOUR AU - Bagnato, A. AU - Salani, D. AU - Castro, V. AU - Wu-Wong, J. R. AU - Tecce, R. AU - Nicotra, M. R. AU - Venuti, A. AU - Natali, P. G. PY - 1999 DA - 1999// TI - Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth JO - Cancer Res VL - 59 ID - Bagnato1999 ER - TY - JOUR AU - Shichiri, M. AU - Hirata, Y. AU - Nakajima, T. AU - Andok, K. AU - Imai, T. AU - Yanagisawa, M. AU - Masaki, T. AU - Marumo, F. PY - 1991 DA - 1991// TI - Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines JO - J Clin Investig VL - 87 UR - https://doi.org/10.1172/JCI115210 DO - 10.1172/JCI115210 ID - Shichiri1991 ER - TY - JOUR AU - Furth, N. AU - Aylon, Y. AU - Oren, M. PY - 2018 DA - 2018// TI - p53 shades of Hippo JO - Cell Death Diff VL - 25 UR - https://doi.org/10.1038/cdd.2017.163 DO - 10.1038/cdd.2017.163 ID - Furth2018 ER - TY - JOUR AU - Ferraiuolo, M. AU - Verduci, L. AU - Blandino, G. AU - Strano, S. PY - 2017 DA - 2017// TI - Mutant p53 protein and the hippo transducers YAP and TAZ: a critical oncogenic node in human cancers JO - Int J Mol Sci VL - 18 UR - https://doi.org/10.3390/ijms18050961 DO - 10.3390/ijms18050961 ID - Ferraiuolo2017 ER - TY - JOUR AU - Agostino, S. AU - Sorrentino, G. AU - Ingallina, E. AU - Valenti, F. AU - Ferraiuolo, M. AU - Bicciato, S. PY - 2017 DA - 2017// TI - YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins JO - EMBO Rep VL - 17 UR - https://doi.org/10.15252/embr.201540488 DO - 10.15252/embr.201540488 ID - Agostino2017 ER - TY - JOUR AU - Lo Sardo, F. AU - Strano, S. AU - Blandino, G. PY - 2018 DA - 2018// TI - YAP and TAZ in lung cancer: oncogenomic role and clinical targeting JO - Cancers VL - 10 UR - https://doi.org/10.3390/cancers10050137 DO - 10.3390/cancers10050137 ID - Lo Sardo2018 ER - TY - JOUR AU - Blandino, G. AU - Agostino, S. PY - 2018 DA - 2018// TI - New therapeutic strategies to treat human cancers expressing mutant p53 proteins JO - J Exp Clin Cancer Res VL - 37 UR - https://doi.org/10.1186/s13046-018-0705-7 DO - 10.1186/s13046-018-0705-7 ID - Blandino2018 ER - TY - JOUR AU - Yoshida, G. J. PY - 2020 DA - 2020// TI - Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways JO - J Exp Clin Cancer Res VL - 39 UR - https://doi.org/10.1186/s13046-020-01611-0 DO - 10.1186/s13046-020-01611-0 ID - Yoshida2020 ER - TY - JOUR AU - Pan, Z. AU - Tian, Y. AU - Cao, C. AU - Niu, G. PY - 2019 DA - 2019// TI - The emerging role of YAP/TAZ in tumor immunity JO - Mol Cancer Res VL - 17 UR - https://doi.org/10.1158/1541-7786.MCR-19-0375 DO - 10.1158/1541-7786.MCR-19-0375 ID - Pan2019 ER - TY - JOUR AU - Moya, I. M. AU - Castaldo, S. A. AU - Mooter, L. AU - Soheily, S. AU - Sansores-Garcia, L. AU - Jacobs, J. PY - 2019 DA - 2019// TI - Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice JO - Science VL - 366 UR - https://doi.org/10.1126/science.aaw9886 DO - 10.1126/science.aaw9886 ID - Moya2019 ER - TY - JOUR AU - White, S. M. AU - Murakami, S. AU - Yi, C. PY - 2019 DA - 2019// TI - The complex entanglement of Hippo-Yap/Taz signaling in tumor immunity JO - Oncogene VL - 38 UR - https://doi.org/10.1038/s41388-018-0649-6 DO - 10.1038/s41388-018-0649-6 ID - White2019 ER - TY - JOUR AU - Kim, M. H. AU - Kim, C. G. AU - Kim, S. -. K. AU - Shin, S. J. AU - Choe, E. A. AU - Park, S. -. H. PY - 2018 DA - 2018// TI - YAP-induced PD-L1 expression drives immune evasion in BRAFi-resistant melanoma JO - Cancer Immunol Res VL - 6 UR - https://doi.org/10.1158/2326-6066.CIR-17-0320 DO - 10.1158/2326-6066.CIR-17-0320 ID - Kim2018 ER - TY - JOUR AU - Lee, B. S. AU - Park, D. AU - Il, Lee, D. H. AU - Lee, J. E. AU - Yeo, M. AU - Park, Y. H. PY - 2017 DA - 2017// TI - Hippo effector YAP directly regulates the expression of PD-L1 transcripts in EGFR-TKI-resistant lung adenocarcinoma JO - Biochem Biophys Res Commun VL - 491 UR - https://doi.org/10.1016/j.bbrc.2017.07.007 DO - 10.1016/j.bbrc.2017.07.007 ID - Lee2017 ER - TY - STD TI - Janse van Rensburg HJ, Azad T, Ling M, Hao Y, Snetsinger B, Khanal P, et al. The Hippo pathway component TAZ promotes immune evasion in human cancer through PD-L1. Cancer Res. 2018;78:1457–70. ID - ref111 ER - TY - JOUR AU - Dupont, S. AU - Morsut, L. AU - Aragona, M. AU - Enzo, E. AU - Giulitti, S. AU - Cordenonsi, M. PY - 2011 DA - 2011// TI - Role of YAP/TAZ in mechanotransduction JO - Nature VL - 474 UR - https://doi.org/10.1038/nature10137 DO - 10.1038/nature10137 ID - Dupont2011 ER - TY - JOUR AU - Calvo, F. AU - Ege, N. AU - Grande-Garcia, A. AU - Hooper, S. AU - Jenkins, R. P. AU - Chaudhry, S. I. PY - 2013 DA - 2013// TI - Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts JO - Nat Cell Biol VL - 15 UR - https://doi.org/10.1038/ncb2756 DO - 10.1038/ncb2756 ID - Calvo2013 ER - TY - JOUR AU - Foster, C. T. AU - Gualdrini, F. AU - Treisman, R. PY - 2017 DA - 2017// TI - Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics JO - Genes Dev VL - 31 UR - https://doi.org/10.1101/gad.304501.117 DO - 10.1101/gad.304501.117 ID - Foster2017 ER - TY - JOUR AU - Liu, F. AU - Lagares, D. AU - Choi, K. M. AU - Stopfer, L. AU - Marinković, A. AU - Vrbanac, V. PY - 2015 DA - 2015// TI - Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis JO - Am J Physiol Cell Mol Physiol VL - 308 UR - https://doi.org/10.1152/ajplung.00300.2014 DO - 10.1152/ajplung.00300.2014 ID - Liu2015 ER - TY - JOUR AU - Ferrari, N. AU - Ranftl, R. AU - Chicherova, I. AU - Slaven, N. D. AU - Moeendarbary, E. AU - Farrugia, A. J. PY - 2019 DA - 2019// TI - Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts JO - Nat Commun VL - 10 UR - https://doi.org/10.1038/s41467-018-07987-0 DO - 10.1038/s41467-018-07987-0 ID - Ferrari2019 ER - TY - JOUR AU - Gao, J. AU - He, L. AU - Zhou, L. AU - Jing, Y. AU - Wang, F. AU - Shi, Y. PY - 2020 DA - 2020// TI - Mechanical force regulation of YAP by F-actin and GPCR revealed by super-resolution imaging JO - Nanoscale VL - 12 UR - https://doi.org/10.1039/C9NR09452K DO - 10.1039/C9NR09452K ID - Gao2020 ER - TY - JOUR AU - Onken, M. D. AU - Makepeace, C. M. AU - Kaltenbronn, K. M. AU - Kanai, S. M. AU - Todd, T. D. AU - Wang, S. PY - 2018 DA - 2018// TI - Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells JO - Sci Signal VL - 11 UR - https://doi.org/10.1126/scisignal.aao6852 DO - 10.1126/scisignal.aao6852 ID - Onken2018 ER - TY - JOUR AU - Annala, S. AU - Feng, X. AU - Shridhar, N. AU - Eryilmaz, F. AU - Patt, J. AU - Yang, J. H. PY - 2019 DA - 2019// TI - Direct targeting of Gαq and Gα11 oncoproteins in cancer cells JO - Sci Signal VL - 12 UR - https://doi.org/10.1126/scisignal.aau5948 DO - 10.1126/scisignal.aau5948 ID - Annala2019 ER - TY - JOUR AU - Sorrentino, G. AU - Ruggeri, N. AU - Specchia, V. AU - Cordenonsi, M. AU - Mano, M. AU - Dupont, S. PY - 2014 DA - 2014// TI - Metabolic control of YAP and TAZ by the mevalonate pathway JO - Nat Cell Biol VL - 16 UR - https://doi.org/10.1038/ncb2936 DO - 10.1038/ncb2936 ID - Sorrentino2014 ER - TY - JOUR AU - Oku, Y. AU - Nishiya, N. AU - Shito, T. AU - Yamamoto, R. AU - Yamamoto, Y. AU - Oyama, C. PY - 2015 DA - 2015// TI - Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers JO - FEBS Open Bio VL - 5 UR - https://doi.org/10.1016/j.fob.2015.06.007 DO - 10.1016/j.fob.2015.06.007 ID - Oku2015 ER - TY - JOUR AU - Xiao, K. AU - Sun, J. PY - 2018 DA - 2018// TI - Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics JO - Cell Signal VL - 41 UR - https://doi.org/10.1016/j.cellsig.2017.09.013 DO - 10.1016/j.cellsig.2017.09.013 ID - Xiao2018 ER - TY - JOUR AU - Davenport, A. P. AU - Kuc, R. E. AU - Southan, C. AU - Maguire, J. J. PY - 2018 DA - 2018// TI - New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine JO - Physiol Res VL - 67 UR - https://doi.org/10.33549/physiolres.933872 DO - 10.33549/physiolres.933872 ID - Davenport2018 ER - TY - JOUR AU - Kim, S. J. AU - Kim, J. S. AU - Kim, S. W. AU - Brantley, E. AU - Yun, S. J. AU - He, J. PY - 2011 DA - 2011// TI - Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer JO - Neoplasia VL - 13 UR - https://doi.org/10.1593/neo.10806 DO - 10.1593/neo.10806 ID - Kim2011 ER - TY - JOUR AU - Kim, S. J. AU - Kim, J. S. AU - Kim, S. W. AU - Yun, S. J. AU - He, J. AU - Brantley, E. PY - 2012 DA - 2012// TI - Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist JO - Transl Oncol VL - 5 UR - https://doi.org/10.1593/tlo.11286 DO - 10.1593/tlo.11286 ID - Kim2012 ER - TY - JOUR AU - Kim, S. J. AU - Lee, H. J. AU - Kim, M. S. AU - Choi, H. J. AU - He, J. AU - Wu, Q. PY - 2015 DA - 2015// TI - Macitentan, a dual endothelin receptor antagonist, in combination with temozolomide leads to glioblastoma regression and long-term survival in mice JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-14-3195 DO - 10.1158/1078-0432.CCR-14-3195 ID - Kim2015 ER - TY - JOUR AU - Lee, H. J. AU - Hanibuchi, M. AU - Kim, S. J. AU - Yu, H. AU - Kim, M. S. AU - He, J. PY - 2016 DA - 2016// TI - Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel JO - Neuro Oncol VL - 18 UR - https://doi.org/10.1093/neuonc/now037 DO - 10.1093/neuonc/now037 ID - Lee2016 ER - TY - JOUR AU - Askoxylakis, V. AU - Ferraro, G. B. AU - Badeaux, M. AU - Kodack, D. P. AU - Kirst, I. AU - Shankaraiah, R. C. PY - 2019 DA - 2019// TI - Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer JO - NPJ Breast Cancer VL - 5 UR - https://doi.org/10.1038/s41523-018-0100-8 DO - 10.1038/s41523-018-0100-8 ID - Askoxylakis2019 ER - TY - JOUR AU - Dhaun, N. AU - Webb, D. J. PY - 2019 DA - 2019// TI - Endothelins in cardiovascular biology and therapeutics JO - Nat Rev Cardiol VL - 16 UR - https://doi.org/10.1038/s41569-019-0176-3 DO - 10.1038/s41569-019-0176-3 ID - Dhaun2019 ER - TY - JOUR AU - Magdeldin, T. AU - López-Dávila, V. AU - Pape, J. AU - Cameron, G. W. W. AU - Emberton, M. AU - Loizidou, M. PY - 2017 DA - 2017// TI - Engineering a vascularised 3D in vitro model of cancer progression JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep44045 DO - 10.1038/srep44045 ID - Magdeldin2017 ER - TY - JOUR AU - Palikuqi, B. AU - Nguyen, D. T. AU - Li, G. AU - Schreiner, R. AU - Pellegata, A. F. AU - Liu, Y. PY - 2020 DA - 2020// TI - Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis JO - Nature VL - 585 UR - https://doi.org/10.1038/s41586-020-2712-z DO - 10.1038/s41586-020-2712-z ID - Palikuqi2020 ER -