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Table 1 IC50 of PLX4032

From: Vitamin C sensitizes BRAFV600E thyroid cancer to PLX4032 via inhibiting the feedback activation of MAPK/ERK signal by PLX4032

Cell lines

VC(0.1 mM)

IC50(μM)

95% CI of IC50(μM)

8505C

–

17.39

13.34–22.67

+

9.21

7.50–11.31

BCPAP

–

4.75

3.95–5.72

+

2.43

1.95–3.04

8305C

–

7.56

5.98–9.54

+

3.14

2.61–3.79

  1. The IC50 of PLX4032 was calculated in different cancer cells with or without the presence of Vitamin C
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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