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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Long noncoding RNA SNHG14 promotes hepatocellular carcinoma progression by regulating miR-876-5p/SSR2 axis

Fig. 3

SNHG14 functions as a sponge for miR-876-5p in HCC cells. a The predicted binding sites of SNHG14 and miR-876-5p from LncBase Predicted v.2. b Relative luciferase activities of SNHG14-WT and SNHG14-MUT reporter were determined with miR-876-5p mimic and miR-NC co-transfection, respectively. c The enrichment of SNHG14 and miR-876-5p in RISC was identified with Ago2-RIP assay. d Quantitative PCR analysis of miR-876-5p after transfected with siSNHG14 and pcDNA3.1/SNHG14, respectively. e miR-876-5p in HCC specimens was analyzed by qPCR (n = 66). f Correlation between SNHG14 and miR-876-5p expression in paired HCC tissues. *P < 0.05, **P < 0.01, ***P < 0.001

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