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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors

Fig. 5

Anti-tumor activity of The-0504 in a pancreatic cancer PDX model. a Tumor-growth curves for each mouse group are indicated. Student’s t-test was used to determine statistical significance. Control vs The-0504 and Nab-paclitaxel vs The-0504: ***p < 0.0001. b Survival curves of different animal groups. Animals were sacrificed when the tumor had reached a volume of about 1000 mm3. Statistical analysis was performed by log-rank test. Control vs The-0504: *p ≤ 0.03; Nab-paclitaxel vs The-0504: *p ≤ 0.03. Arrows indicate the six days during which treatment was administered

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