Fig. 3

LINC00680 promotes HCC chemoresistance to 5-Fu in vitro and in vivo. a, b. Colony formation of7 sh-LINC00680-transfected cells after treatment with 5-Fu. c. Colony formation of LINC00680 overexpression plasmid-transfected cells after treatment with 5-Fu. d, e. Cell viability analysis using CCK8 in sh-LINC00680-transfected SNU-449 and SK-hep1 cells under different concentrations of 5-Fu. f. Cell viability analysis using CCK8 in LINC00680 overexpression plasmid-transfected Huh-7 cells under different concentrations of 5-Fu. g, h. Representative images of xenograft tumors of shLINC0068-transfected HCC cells in nude mice following intraperitoneal injection of 5-Fu. i, j. Tumor weight of sh-LINC00680- or sh-NC-transfected cells in nude mice after treatment with 5-Fu. k, l. Tumor growth curves of sh-LINC00680- or sh-NC-transfected cells in nude mice after treatment with 5-Fu during the indicated days. m. Ki67 expression in sh-LINC00680- or sh-NC-transfected cells in nude mice after treatment with 5-Fu. ^**P < 0.01