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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification

Fig. 6

LINC00460 governs CRC growth and metastasis by stabilizing HMGA1 mRNA in vitro. a The HMGA1 protein level analyzed by Western blot after re-express HMGA1 in LINC00460 KD CRC cells. b, c Colony formation assays for effects of HMGA1 re-expression on proliferation of HCT116 and SW480 cells with LINC00460 KD (**p < 0.01, ***p < 0.001). d, e Effects of HMGA1 re-expression on migration and invasion of HCT116 and SW480 cells with LINC00460 KD (**p < 0.01, ***p < 0.001)

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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