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Table 1 Comparison of clinical features between LUAD patients with low and high ESCO2 levels in TCGA database

From: ESCO2 promotes lung adenocarcinoma progression by regulating hnRNPA1 acetylation

Clinical character#

Clinical

groups

ESCO2

x2

p value

High

(n = 155) (%)

-Low

(n = 155) (%)

Age (years)

≤ 60

54 (34.8)

41 (26.5)

2.611

0.106

>  60

95 (61.3)

108 (69.7)

Gender***

Male

91 (58.7)

59 (38.1)

13.23

< 0.001

Female

64 (41.3)

96 (61.9)

ALK Translocation

No

54 (34.8)

71 (45.8)

0.377

0.539

Yes

12 (7.7)

12 (7.7)

pT status***

T1 T2 ~ T4

37 (23.9)

66 (42.6)

12.27

< 0.001

117 (75.5)

88 (56.8)

pN status**

N0

88 (56.8)

110 (71.0)

8.771

0.003

N1 ~ N2

66 (42.6)

40 (25.8)

pM status*

M0

106 (68.4)

101 (65.2)

4.026

0.045

M1

13 (8.4)

4 (2.6)

Recurred/Progressed**

No

62 (40.0)

88 (56.8)

8.317

0.004

Yes

67 (43.2)

46 (29.7)

Clinical Stage**

Stage I ~ IIA

83 (53.5)

106 (68.4)

7.761

0.005

Stage IIB ~ IV

70 (45.2)

46 (29.7)

  1. Differences with *p<0.05, **p<0.01 or ***p<0.001 were considered statistically significant
  2. #American Joint Committee on Cancer classification (Version 7) (AJCC)