TY - JOUR AU - Bray, F. AU - Ferlay, J. AU - Soerjomataram, I. AU - Siegel, R. L. AU - Torre, L. A. AU - Jemal, A. PY - 2018 DA - 2018// TI - Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries JO - CA Cancer J Clin VL - 68 UR - https://doi.org/10.3322/caac.21492 DO - 10.3322/caac.21492 ID - Bray2018 ER - TY - JOUR AU - Huang, L. -. Y. AU - Zhao, J. AU - Chen, H. AU - Wan, L. AU - Inuzuka, H. AU - Guo, J. PY - 2018 DA - 2018// TI - SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis JO - Nat Commun VL - 9 UR - https://doi.org/10.1038/s41467-018-06038-y DO - 10.1038/s41467-018-06038-y ID - Huang2018 ER - TY - JOUR AU - Schuhmacher, C. AU - Gretschel, S. AU - Lordick, F. AU - Reichardt, P. AU - Hohenberger, W. AU - Eisenberger, C. F. PY - 2010 DA - 2010// TI - Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer randomized trial 40954 JO - J Clin Oncol VL - 28 UR - https://doi.org/10.1200/JCO.2009.26.6114 DO - 10.1200/JCO.2009.26.6114 ID - Schuhmacher2010 ER - TY - JOUR AU - Coburn, N. AU - Cosby, R. AU - Klein, L. AU - Knight, G. AU - Malthaner, R. AU - Mamazza, J. PY - 2018 DA - 2018// TI - Staging and surgical approaches in gastric cancer: a systematic review JO - Cancer Treat Rev VL - 63 UR - https://doi.org/10.1016/j.ctrv.2017.12.006 DO - 10.1016/j.ctrv.2017.12.006 ID - Coburn2018 ER - TY - JOUR AU - Cutsem, E. AU - Sagaert, X. AU - Topal, B. AU - Haustermans, K. AU - Prenen, H. PY - 2016 DA - 2016// TI - Gastric cancer JO - Lancet. VL - 388 UR - https://doi.org/10.1016/S0140-6736(16)30354-3 DO - 10.1016/S0140-6736(16)30354-3 ID - Cutsem2016 ER - TY - JOUR AU - Fontana, E. AU - Smyth, E. C. PY - 2016 DA - 2016// TI - Novel targets in the treatment of advanced gastric cancer: a perspective review JO - Ther Adv Med Oncol VL - 8 UR - https://doi.org/10.1177/1758834015616935 DO - 10.1177/1758834015616935 ID - Fontana2016 ER - TY - JOUR AU - Bernards, N. AU - Creemers, G. J. AU - Nieuwenhuijzen, G. A. P. AU - Bosscha, K. AU - Pruijt, J. F. M. AU - Lemmens, V. E. P. P. PY - 2013 DA - 2013// TI - No improvement in median survival for patients with metastatic gastric cancer despite increased use of chemotherapy JO - Ann Oncol VL - 24 UR - https://doi.org/10.1093/annonc/mdt401 DO - 10.1093/annonc/mdt401 ID - Bernards2013 ER - TY - JOUR AU - Li, B. AU - Huang, Q. AU - Wei, G. -. H. PY - 2019 DA - 2019// TI - The role of HOX transcription factors in Cancer predisposition and progression JO - Cancers (Basel) VL - 11 UR - https://doi.org/10.3390/cancers11040528 DO - 10.3390/cancers11040528 ID - Li2019 ER - TY - STD TI - Song C, Han Y, Luo H, Qin Z, Chen Z, Liu Y, et al. HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer. Cancer Med. 2019;8(12):5651–61. ID - ref9 ER - TY - JOUR AU - Lim, J. Y. AU - Yoon, S. O. AU - Seol, S. -. Y. AU - Hong, S. W. AU - Kim, J. W. AU - Choi, S. H. PY - 2013 DA - 2013// TI - Overexpression of miR-196b and HOXA10 characterize a poor-prognosis gastric cancer subtype JO - World J Gastroenterol VL - 19 UR - https://doi.org/10.3748/wjg.v19.i41.7078 DO - 10.3748/wjg.v19.i41.7078 ID - Lim2013 ER - TY - JOUR AU - Santamaria, P. G. AU - Moreno-Bueno, G. AU - Portillo, F. AU - Cano, A. PY - 2017 DA - 2017// TI - EMT: Present and future in clinical oncology JO - Mol Oncol VL - 11 UR - https://doi.org/10.1002/1878-0261.12091 DO - 10.1002/1878-0261.12091 ID - Santamaria2017 ER - TY - JOUR AU - Dongre, A. AU - Weinberg, R. A. PY - 2019 DA - 2019// TI - New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer JO - Nat Rev Mol Cell Biol VL - 20 UR - https://doi.org/10.1038/s41580-018-0080-4 DO - 10.1038/s41580-018-0080-4 ID - Dongre2019 ER - TY - JOUR AU - Colak, S. AU - Dijke, P. PY - 2017 DA - 2017// TI - Targeting TGF-β signaling in Cancer JO - Trends Cancer VL - 3 UR - https://doi.org/10.1016/j.trecan.2016.11.008 DO - 10.1016/j.trecan.2016.11.008 ID - Colak2017 ER - TY - JOUR AU - Thiery, J. P. AU - Acloque, H. AU - Huang, R. Y. J. AU - Nieto, M. A. PY - 2009 DA - 2009// TI - Epithelial-mesenchymal transitions in development and disease JO - Cell. VL - 139 UR - https://doi.org/10.1016/j.cell.2009.11.007 DO - 10.1016/j.cell.2009.11.007 ID - Thiery2009 ER - TY - STD TI - Xu G, Chen Y, Fu M, Zang X, Cang M, Niu Y, et al. Circular RNA CCDC66 promotes gastric cancer progression by regulating c-Myc and TGF-β signaling pathways. J Cancer. 2020;11(10):2759–68. ID - ref15 ER - TY - JOUR AU - Xiong, R. AU - Gao, J. -. L. AU - Yin, T. PY - 2019 DA - 2019// TI - G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer JO - Onco Targets Ther VL - 12 UR - https://doi.org/10.2147/OTT.S213728 DO - 10.2147/OTT.S213728 ID - Xiong2019 ER - TY - JOUR AU - Jeong, M. -. H. AU - Park, S. -. Y. AU - Lee, S. -. H. AU - Seo, J. S. AU - Yoo, J. -. Y. AU - Park, S. -. H. PY - 2019 DA - 2019// TI - EPB41L5 mediates TGFβ-induced metastasis of gastric Cancer JO - Clin Cancer Res VL - 25 UR - https://doi.org/10.1158/1078-0432.CCR-18-2959 DO - 10.1158/1078-0432.CCR-18-2959 ID - Jeong2019 ER - TY - JOUR AU - Sang Cheul, O. AU - Sohn, B. H. AU - Cheong, J. -. H. AU - Kim, S. -. B. AU - Lee, J. E. AU - Park, K. C. PY - 2018 DA - 2018// TI - Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype JO - Nat Commun VL - 9 UR - https://doi.org/10.1038/s41467-018-04179-8 DO - 10.1038/s41467-018-04179-8 ID - Sang Cheul2018 ER - TY - JOUR AU - Yang, B. W. AU - Bai, J. AU - Shi, R. AU - Shao, X. AU - Yang, Y. AU - Jin, Y. PY - 2020 DA - 2020// TI - TGFB2 serves as a link between epithelial-mesenchymal transition and tumor mutation burden in gastric cancer JO - Int Immunopharmacol VL - 84 UR - https://doi.org/10.1016/j.intimp.2020.106532 DO - 10.1016/j.intimp.2020.106532 ID - Yang2020 ER - TY - JOUR AU - Shah, C. A. AU - Wang, H. AU - Bei, L. AU - Platanias, L. C. AU - Eklund, E. A. PY - 2011 DA - 2011// TI - HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M110.183251 DO - 10.1074/jbc.M110.183251 ID - Shah2011 ER - TY - JOUR AU - Lin, Y. -. T. AU - Kou-Juey, W. PY - 2020 DA - 2020// TI - Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling JO - J Biomed Sci VL - 27 UR - https://doi.org/10.1186/s12929-020-00632-3 DO - 10.1186/s12929-020-00632-3 ID - Lin2020 ER - TY - JOUR AU - Angela Nieto, M. AU - Huang, R. Y. -. J. AU - Jackson, R. A. AU - Thiery, J. P. PY - 2016 DA - 2016// TI - EMT: 2016 JO - Cell. VL - 166 UR - https://doi.org/10.1016/j.cell.2016.06.028 DO - 10.1016/j.cell.2016.06.028 ID - Angela Nieto2016 ER - TY - JOUR AU - Bertero, A. AU - Brown, S. AU - Madrigal, P. AU - Osnato, A. AU - Ortmann, D. AU - Yiangou, L. PY - 2018 DA - 2018// TI - The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency JO - Nature. VL - 555 UR - https://doi.org/10.1038/nature25784 DO - 10.1038/nature25784 ID - Bertero2018 ER - TY - JOUR AU - Chen, M. AU - Wei, L. AU - Law, C. -. T. AU - Tsang, F. H. -. C. AU - Shen, J. AU - Cheng, C. L. -. H. PY - 2018 DA - 2018// TI - RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2 JO - Hepatology. VL - 67 UR - https://doi.org/10.1002/hep.29683 DO - 10.1002/hep.29683 ID - Chen2018 ER - TY - STD TI - Lin S, Choe J, Peng D, Triboulet R, Gregory RI. The m(6) A methyltransferase METTL3 promotes translation in human Cancer cells. Mol Cell. 2016;62(3):335–45. ID - ref25 ER - TY - JOUR AU - Wang, Q. AU - Geng, W. AU - Guo, H. AU - Wang, Z. AU - Xu, K. AU - Chen, C. PY - 2020 DA - 2020// TI - Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer JO - J Hematol Oncol VL - 13 UR - https://doi.org/10.1186/s13045-020-00895-1 DO - 10.1186/s13045-020-00895-1 ID - Wang2020 ER - TY - STD TI - Wang H, Hu X, Huang M, Liu J, Gu Y, Ma L, et al. Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. Nat Commun. 2019;10(1):1898. ID - ref27 ER - TY - JOUR AU - Chen, Y. AU - Peng, C. AU - Chen, J. AU - Chen, D. AU - Yang, B. AU - He, B. PY - 2019 DA - 2019// TI - WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1 JO - Mol Cancer VL - 18 UR - https://doi.org/10.1186/s12943-019-1053-8 DO - 10.1186/s12943-019-1053-8 ID - Chen2019 ER - TY - STD TI - Yu X, Zhao H, Cao Z. The m6A methyltransferase METTL3 aggravates the progression of nasopharyngeal carcinoma through inducing EMT by m6A-modified snail mRNA. Minerva Med. 2020. https://doi.org/10.23736/S0026-4806.20.06653-7. Online ahead of print. ID - ref29 ER - TY - JOUR AU - Hua, W. AU - Zhao, Y. AU - Jin, X. AU - Yu, D. AU - He, J. AU - Xie, D. PY - 2018 DA - 2018// TI - METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition JO - Gynecol Oncol VL - 151 UR - https://doi.org/10.1016/j.ygyno.2018.09.015 DO - 10.1016/j.ygyno.2018.09.015 ID - Hua2018 ER - TY - JOUR AU - Liu, T. AU - Yang, S. AU - Sui, J. AU - Xu, S. -. Y. AU - Cheng, Y. -. P. AU - Shen, B. PY - 2020 DA - 2020// TI - Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer JO - J Cell Physiol VL - 235 UR - https://doi.org/10.1002/jcp.28994 DO - 10.1002/jcp.28994 ID - Liu2020 ER - TY - JOUR AU - Xu, H. AU - Wang, H. AU - Zhao, W. AU - Sirui, F. AU - Li, Y. AU - Ni, W. PY - 2020 DA - 2020// TI - SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating snail mRNA homeostasis in hepatocellular carcinoma JO - Theranostics. VL - 10 UR - https://doi.org/10.7150/thno.42539 DO - 10.7150/thno.42539 ID - Xu2020 ER - TY - JOUR AU - Lin, X. AU - Chai, G. AU - Wu, Y. AU - Li, J. AU - Chen, F. AU - Liu, J. PY - 2019 DA - 2019// TI - RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of snail JO - Nat Commun VL - 10 UR - https://doi.org/10.1038/s41467-019-09865-9 DO - 10.1038/s41467-019-09865-9 ID - Lin2019 ER - TY - STD TI - Yuan C, Zhu X, Han Y, Song C, Liu C, Lu S, et al. Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1. J Exp Clin Cancer Res. 2016;35:15. ID - ref34 ER - TY - JOUR AU - Cui, Y. -. P. AU - Xie, M. AU - Pan, W. -. X. AU - Zhang, Z. -. Y. AU - Li, W. -. F. PY - 2020 DA - 2020// TI - HOXA10 promotes the development of bladder cancer through regulating FOSL1 JO - Eur Rev Med Pharmacol Sci VL - 24 ID - Cui2020 ER - TY - JOUR AU - Zhang, Y. AU - Chen, J. AU - Wu, S. -. S. AU - Lv, M. -. J. AU - Yu, Y. -. S. AU - Tang, Z. -. H. PY - 2019 DA - 2019// TI - HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1 JO - Cancer Manag Res VL - 11 UR - https://doi.org/10.2147/CMAR.S199239 DO - 10.2147/CMAR.S199239 ID - Zhang2019 ER - TY - STD TI - Chen W, Wu G, Zhu Y, Zhang W, Zhang H, Zhou Y, et al. HOXA10 deteriorates gastric cancer through activating JAK1/STAT3 signaling pathway. Cancer Manag Res. 2019;11:6625–35. ID - ref37 ER - TY - JOUR AU - Bure, I. V. AU - Nemtsova, M. V. AU - Zaletaev, D. V. PY - 2019 DA - 2019// TI - Roles of E-cadherin and Noncoding RNAs in the Epithelial-mesenchymal Transition and Progression in Gastric Cancer JO - Int J Mol Sci VL - 20 UR - https://doi.org/10.3390/ijms20122870 DO - 10.3390/ijms20122870 ID - Bure2019 ER - TY - JOUR AU - Jackstadt, R. AU - Hooff, S. R. AU - Leach, J. D. AU - Cortes-Lavaud, X. AU - Lohuis, J. O. AU - Ridgway, R. A. PY - 2019 DA - 2019// TI - Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis JO - Cancer Cell VL - 36 UR - https://doi.org/10.1016/j.ccell.2019.08.003 DO - 10.1016/j.ccell.2019.08.003 ID - Jackstadt2019 ER - TY - JOUR AU - Zhang, Z. AU - Deng, Y. AU - Zheng, G. AU - Jia, X. AU - Xiong, Y. AU - Luo, K. PY - 2017 DA - 2017// TI - SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer JO - Oncogenesis. VL - 6 UR - https://doi.org/10.1038/oncsis.2017.53 DO - 10.1038/oncsis.2017.53 ID - Zhang2017 ER - TY - JOUR AU - Lan, Q. AU - Liu, P. Y. AU - Haase, J. AU - Bell, J. L. AU - Hüttelmaier, S. AU - Liu, T. PY - 2019 DA - 2019// TI - The critical role of RNA m6A methylation in Cancer JO - Cancer Res VL - 79 UR - https://doi.org/10.1158/0008-5472.CAN-18-2965 DO - 10.1158/0008-5472.CAN-18-2965 ID - Lan2019 ER -