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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Long non-coding RNA MAPKAPK5-AS1/PLAGL2/HIF-1α signaling loop promotes hepatocellular carcinoma progression

Fig. 2

MAPKAPK5-AS1 promotes proliferation and inhibits apoptosis of HCC cells. a-b MTT assay was carried out to examined the effect of MAPKAPK5-AS1 knockdown or overexpression on HCC cells viability. c-d Colony formation confirmed the negative regulatory effect of MAPKAPK5-AS1 on tumor cells proliferation. e-f The influence of MAPKAPK5-AS1 on DNA synthesis activity of HCC cell was evaluated by EdU assay. g-h The effect of MAPKAPK5-AS1 on cell apoptosis was assessed by flow cytometry. *p < 0.05

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