Fig. 6

MiR-154-5p mediates the function of MAPKAPK5-AS1. a-c MTT, colony formation and EdU assays were conducted to explore the effect of miR-154-5p inhibitors on cell proliferation suppressed by MAPKAPK5-AS1 knockdown. d Flow cytometry showed the effect of miR-154-5p inhibitors on apoptosis induced by MAPKAPK5-AS1 knockdown. e-f Transwell assay were performed to evaluate the effects of miR-154-5p inhibitors on the tumor cells abilities of migration and invasion impaired by MAPKAPK5-AS1 kmockdown. c-d Expression of EMT markers was detected by western blotting to assess the effect of miR-154-5p inhibitors on EMT process inhibited by MAPKAPK5-AS1 knockdown. *p < 0.05