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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway

Fig. 1

CAFs induced radioresistance of tumor cells. a and b RSI scores of tumors with abundant CAF infiltration were higher than the group with low CAF infiltration based on TCGA database and GSE12452 dataset, respectively. c HE staining showed the infiltration of CAFs in NPC tissue. d and e IHC showed greater CAF infiltration in radioresistant NPC tissue. f and g Western blot and immunofluorescence assay showed that CAFs expressed higher levels of α-SMA than NFs. h-j CAFs induced radioresistance of NPC cells. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001, ns, no significance

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