Fig. 3

CPSF6 promotes migration, invasion and metastasis of HCC cells. a Effect of CPSF6 overexpression on HL-7702 cell migration. b Effect of CPSF6 knockdown on Huh-7 cell migration. c Effect of CPSF6 overexpression on HL-7702 cell invasion. d Effect of CPSF6 knockdown on Huh-7 cell invasion. Representative pictures of H&E staining of lungs and incidence of lung metastasis from mice inoculated with (e) HL-7702 and (f) Huh-7 cells. Red arrows indicated the lung metastases. Results represented mean ± SD using bar graph. Scale bars, 100 μm. **p < 0.001, Student’s t test