Fig. 8

Expression of NQO1 in human HCC tissues. a IHC staining of NQO1 in surrounding non-tumor and HCC tissues. Scale bar, 50 μm. b Western blot analysis of NQO1 expression in 16 paired surrounding non-tumor (N) and HCC tumor (T) tissues. β-actin was used as internal control. c The correlation analysis between NQO1 expression and CPSF6 level in 124 HCC tissues (TNM, III/IV) with linear regression and pearson’s correlation significance (P < 0.0001, ANOVA test). d The proposed mechanism of CPSF6 in regulation of HCC progression