TY - JOUR AU - Le Large, T. Y. S. AU - Bijlsma, M. F. AU - El Hassouni, B. AU - Mantini, G. AU - Lagerweij, T. AU - Henneman, A. A. AU - Funel, N. AU - Kok, B. AU - Pham, T. V. AU - de Haas, R. AU - Morelli, L. AU - Knol, J. C. AU - Piersma, S. R. AU - Kazemier, G. AU - van Laarhoven, H. W. M. AU - Giovannetti, E. AU - Jimenez, C. R. PY - 2021 DA - 2021/03/09 TI - Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma JO - Journal of Experimental & Clinical Cancer Research SP - 91 VL - 40 IS - 1 AB - Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth and is regulated by phosphorylation. We investigated phosphorylated kinases as target in PDAC. SN - 1756-9966 UR - https://doi.org/10.1186/s13046-021-01892-z DO - 10.1186/s13046-021-01892-z ID - Le Large2021 ER -