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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: CircFAM73A promotes the cancer stem cell-like properties of gastric cancer through the miR-490-3p/HMGA2 positive feedback loop and HNRNPK-mediated β-catenin stabilization

Fig. 2

CircFAM73A promotes the proliferation and migration of GC in vitro. a Colony formation assay of BGC823 and SGC7901 transfected with control, circFAM73A siRNA, vector or circFAM73A plasmid. b, c CCK-8 and EdU assays were performed to evaluate cell proliferative effects of circFAM73A in BGC823 and SGC7901. Scale bar: 100 μm. d Effects of circFAM73A alteration on the growth of gastric organoids. Scale bar: 25 μm. e Effects of circFAM73A alteration on cell cycle distribution of BGC823 and SGC7901 detected by flow cytometry. f Effects of circFAM73A alteration on cell migration ability were tested by Transwell assay. Scale bar: 100 μm. Graph represents mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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