Skip to main content
Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Elafin promotes tumour metastasis and attenuates the anti-metastatic effects of erlotinib via binding to EGFR in hepatocellular carcinoma

Fig. 1

Elafin is up-regulated and correlates with poor prognosis in HCC. a The representative images of different levels of Elafin expression in HCC (left) and adjacent noncancerous liver tissues (right) detected by the immunohistochemical staining (IHC) are presented. Scale bar, 100 μm. b Quantification of Elafin expression in HCC and peri-tumor tissues according to IHC scores in SYSUCC training cohort (n = 94). Relative IHC scores are shown as mean ± SD. *** P < 0.001, based on the Wilcoxon matched pairs test. c Overall survival (OS) and Recurrence-free survival (RFS) curves with risk tables for patients with high and low Elafin expression in SYSUCC training cohort (n = 94). d Quantification of Elafin expression in HCC and peri-tumor tissues according to IHC scores in SYSUCC validation cohort (n = 378). Relative IHC scores are shown as mean ± SD. *** P < 0.001, based on the Wilcoxon matched pairs test. e OS and RFS curves with risk tables for patients with high and low Elafin expression in SYSUCC validation cohort (n = 378). f Relative of Elafin expression in HCC (n = 371) and normal tissues (n = 50) is determined based on TCGA dataset. *** P < 0.001. g OS curves with risk tables for patients with high and low Elafin expression based on TCGA HCC dataset (n = 371). h OS curves with risk tables for patients with high and low Elafin expression based on GEO database (GSE14520, n = 221)

Back to article page