Fig. 1

miR-106b-5p expression is upregulated in melanoma and an independent risk factor for the survival of patients with melanoma. a The expression of miR-106b-5p was detected in 36 malignant melanoma tissues and adjacent normal tissues. b The miR-106b-5p levels was analyzed by using GEO#GSE34460 dataset. c The miR-106b-5p levels was analyzed through GEO#GSE24996 dataset. d FISH analysis of miR-106b-5p in malignant melanoma tissues and adjacent normal tissues. Scale bar, 100 μm. e The miR-106b-5p expression profile in human melanoma cell lines (A375, A2058, SK-MEL-28, SK-MEL-1) and human epidermal melanocytes (HEMa-LP). f The overall survival curves of melanoma patients with high miR-106b-5p levels and low miR-106b-5p levels. g The prognostic data of melanoma in TCGA by using OncoLnc (http://www.oncolnc.org). Data were expressed as the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001