Fig. 8From: Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myelomaMTT proliferation assay were performed in primary cells from 12 MM patients. a–f MTT proliferation assays were performed in primary cells from six lenalidomide-sensitive MM patients. Cells were treated with 10–50 nM CUDC-907 for 48 h. g-l MTT proliferation assays were performed in primary cells from six lenalidomide-resistant MM patients. Cells were treated with 5 μM lenalidomide, 10 μM lenalidomide, or 10–50 nM CUDC-907 for 48 h. (*p < 0.05, **p < 0.01, “ns” indicates no significant difference.) Clinical parameters of MM patients are shown in Table 1Back to article page