Fig. 1

The effect of ex vivo irradiation on the immune response against melanoma. a to c Luciferase imaging of C57BL/6 a, c and athymic b mice injected in the tail vein with B16/F10 cells. When indicated, cells were irradiated ex vivo (10 Gy; 24 h) or mice were treated with an anti-CD8 antibody c. Total flux (photons/s) analyzes were compared between ex vivo irradiated and non-irradiated groups (ns, no significant). Survival in the melanoma mouse models was examined (Graphs below).p-values indicate significant differences in survival when compared both tested groups. Color scale was set to Min = 1.00e6; Max = 1.00e7 for all pictures