Fig. 3

MAP17 is required for tumor growth in HCC. a The effect of MAP17 knockdown on in vitro proliferation of SMCC-7721 and HCC-LM3 cells was analyzed by colony formation assay (n = 3). b sh-Ctrl and sh-MAP17 SMCC-7721 and HCC-LM3 cells were subcutaneously injected into the nude mice (n = 5 per group); gross xenografts, tumor growth curve, and tumor weight were shown. c The effect of MAP17 or MAP17-PDZm overexpression on the in vitro proliferation of MHCC-97H cells was analyzed by colony formation assay (n = 3). d MHCC-97H cells were cultured in a medium containing galactose (5 mM) but no glucose; the effect of MAP17 overexpression on colony formation ability was further analyzed. *P < 0.05; **P < 0.01; ***P < 0.001