Fig. 8

OXCT1-AS1 promotes the tumorigenesis of GBM cells in vivo. a After constructing intracranial tumour models (6 mice in each group), magnetic resonance imaging on day 15 showed that the tumour size in the sh-OXCT1-AS1 group was dramatically smaller than that in the vector group. b The tumour volume changes were calculated every 4 days. Tumour size = 4/3π(a*b*c), (a,b,c are the 1/2 maximum diameter at coronal, sagittal and axial position). c Survival status of nude mice bearing GBM. d Expression of miR-195 in nude mice was detected by qRT-PCR. e-f Immunohistochemistry of CDC25A in vivo, Scale bars: 150 nm. The bars represent SD (*p < 0.05, **p < 0.01, ***p < 0.001)