Novel LncRNA OXCT1-AS1 indicates poor prognosis and contributes to tumorigenesis by regulating miR-195/CDC25A axis in glioblastoma

Table 2 Univariable and multivariable Cox regression analysis in GBM

Characteristics	Subset	Univariate analysis Hazard ratio (95%CI)	P value	Multivariate analysis Hazard ratio (95%CI)	P value
Age	≤48/> 48	1.378 (0.451–4.214)	0.751	1.794 (0.243–4.241)	0.981
Gender	Male/Female	1.556 (0.643–3.749)	0.327	3.165 (0.981–10.210)	0.885
Chr7 gain/Chr10 loss	Yes/No	0.318 (0.126–0.804)	0.015*	0.908 (0.246–3.358)	0.054
1p/19q status	Code/Noncoded	9.036 (7.841–37.803)	0.000*	4.355 (1.121–16.443)	0.002*
IDH status	Mutation/Wild	0.630 (2.701–3.242)	0.003*	0.170 (0.042–0.691)	0.013*
MGMT promoter status	Mutation/Wild	7.151 (3.606–81.581)	0.011*	5.706 (1.986–34.619)	0.064
OXCT1-AS1	High/Low	0.701 (0.191–0.541)	0.000*	0.468 (0.094–0.361)	0.014*

In both univariable and multivariable Cox regression analyses, all characteristics were evaluated as continuous variables. P < 0.05 was considered statistically significant in all analyses.

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