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Table 1 Relationship of circATP5B expression to clinical features of glioma patients

From: The SRSF1/circATP5B/miR-185-5p/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2/STAT3 signaling pathway

Clinical features Samples (n = 70) CircATP5B expressiona P value
Low (n = 35) High (n = 35)
Sex Male 38 18 20 P = 0.631
Female 32 17 15
Age ≤ 50 28 16 12 P = 0.329
>  50 42 19 23
WHO grade II 20 15 5 P = 0.002
III 25 14 11
IV 25 6 19
IDH
status
Wild 33 9 24 P<0.001
Mutant 37 26 11
1p/19q status Codeletion 38 25 13 P = 0.004
Non-codeletion 32 10 22
H3F3A status Wild 39 24 15 P = 0.03
Mutant 31 11 20
MGMT
status
Methylation 42 26 16 P = 0.015
Unmethylation 28 9 19
  1. a CircATP5B expression was detected by qRT-PCR and ranked from low to high. The high expression of circATP5B was defined as the expression level higher than the median expression level of circATP5B