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Table 2 Radiobiological Parameters

From: ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

Cell lines

N (Mean ± SDa)

D0 (Mean ± SDa)

Dq (Mean ± SDa)

SF2 (Mean ± SDa)

MCF-7-vector

3.06 ± 0.28

1.00 ± 0.05

1.12 ± 0.13

0.36 ± 0.05

MCF-7-ALG3

4.90 ± 0.82

1.42 ± 0.12

2.24 ± 0.05

0.74 ± 0.02

ZR-75-30-vector

2.04 ± 0.35

1.09 ± 0.09

0.76 ± 0.17

0.30 ± 0.04

ZR-75-30-ALG3

4.96 ± 1.22

1.40 ± 0.14

2.20 ± 0.14

0.73 ± 0.03

MDA-MB-231-control

5.48 ± 1.92

1.52 ± 0.14

2.50 ± 0.34

0.81 ± 0.08

MDA-MB-231-sg1

2.10 ± 0.17

1.20 ± 0.17

0.90 ± 0.15

0.36 ± 0.09

MDA-MB-231-sg2

1.63 ± 0.70

1.21 ± 0.08

0.50 ± 0.43

0.28 ± 0.07

SUM159PT-control

3.98 ± 0.44

1.52 ± 0.03

2.10 ± 0.13

0.71 ± 0.03

SUM159PT-sg1

1.59 ± 0.40

1.26 ± 0.06

0.55 ± 0.35

0.30 ± 0.06

SUM159PT-sg2

2.28 ± 0.09

1.17 ± 0.12

0.95 ± 0.15

0.36 ± 0.04

  1. N extrapolation number, D0 mean lethal dose, Dq quasi-threshold Dose, SF2 surviving fraction at 2 Gy
  2. aMean ± SD represents mean values of surviving fractions ± standard deviations