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Table 2 Radiobiological Parameters

From: ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

Cell lines N (Mean ± SDa) D0 (Mean ± SDa) Dq (Mean ± SDa) SF2 (Mean ± SDa)
MCF-7-vector 3.06 ± 0.28 1.00 ± 0.05 1.12 ± 0.13 0.36 ± 0.05
MCF-7-ALG3 4.90 ± 0.82 1.42 ± 0.12 2.24 ± 0.05 0.74 ± 0.02
ZR-75-30-vector 2.04 ± 0.35 1.09 ± 0.09 0.76 ± 0.17 0.30 ± 0.04
ZR-75-30-ALG3 4.96 ± 1.22 1.40 ± 0.14 2.20 ± 0.14 0.73 ± 0.03
MDA-MB-231-control 5.48 ± 1.92 1.52 ± 0.14 2.50 ± 0.34 0.81 ± 0.08
MDA-MB-231-sg1 2.10 ± 0.17 1.20 ± 0.17 0.90 ± 0.15 0.36 ± 0.09
MDA-MB-231-sg2 1.63 ± 0.70 1.21 ± 0.08 0.50 ± 0.43 0.28 ± 0.07
SUM159PT-control 3.98 ± 0.44 1.52 ± 0.03 2.10 ± 0.13 0.71 ± 0.03
SUM159PT-sg1 1.59 ± 0.40 1.26 ± 0.06 0.55 ± 0.35 0.30 ± 0.06
SUM159PT-sg2 2.28 ± 0.09 1.17 ± 0.12 0.95 ± 0.15 0.36 ± 0.04
  1. N extrapolation number, D0 mean lethal dose, Dq quasi-threshold Dose, SF2 surviving fraction at 2 Gy
  2. aMean ± SD represents mean values of surviving fractions ± standard deviations