ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

Table 4 Association between ALG3 expression and other clinicopathologic

Features of breast cancer	No. of patients	ALG3 expression		p values
Features of breast cancer	No. of patients	Low expression	High expression	p values
Age				0.920^†
≤ 50	225	121	104
> 50	151	82	69
Stage (AJCC)				0.010^#
I ~ II	188	114	74
III ~ IV	188	89	99
T				0.017^#
T1 ~ T2	290	164	126
T3 ~ T4	86	39	47
N				0.028^#
N0 ~ N2	205	123	82
N2 ~ N3	171	80	91
Histological grade				0.068^#
1	108	69	39
2	179	88	91
3	89	46	43
ER				0.011^†
Negative	169	79	90
Positive	207	124	83
Missing	0
PR				0.049^†
Negative	124	58	66
Positive	252	145	107
Missing	0
HER2				0.205^†
Negative	211	158	124
Positive	165	45	49
Missing	0
Ki67				0.001^#
Low expression^a	281	161	120
High expression^b	88	42	46
Missing	7
Mutational p53				0.001^#
Low expression^a	196	133	90
High expression^b	165	64	74
Missing	15
VEGF				0.167^#
Low expression^a	302	165	147
High expression^b	64	38	26
Missing	10

†p -values and #p -values were calculated with the chi-square test and continuity correlation, respectively
^aLow expression represented -, +, ++ staining index in IHC examination
^bHigh expression represented +++, ++++ staining index in IHC examination

ISSN: 1756-9966