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Table 4 Association between ALG3 expression and other clinicopathologic

From: ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

Features of breast cancer

No. of patients

ALG3 expression

p values

Low expression

High expression

Age

   

0.920

  ≤ 50

225

121

104

 

  > 50

151

82

69

 

Stage (AJCC)

   

0.010#

 I ~ II

188

114

74

 

 III ~ IV

188

89

99

 

T

   

0.017#

 T1 ~ T2

290

164

126

 

 T3 ~ T4

86

39

47

 

N

   

0.028#

 N0 ~ N2

205

123

82

 

 N2 ~ N3

171

80

91

 

Histological grade

   

0.068#

 1

108

69

39

 

 2

179

88

91

 

 3

89

46

43

 

ER

   

0.011

 Negative

169

79

90

 

 Positive

207

124

83

 

 Missing

0

   

PR

   

0.049

 Negative

124

58

66

 

 Positive

252

145

107

 

 Missing

0

   

HER2

   

0.205

 Negative

211

158

124

 

 Positive

165

45

49

 

 Missing

0

   

Ki67

   

0.001#

 Low expressiona

281

161

120

 

 High expressionb

88

42

46

 

 Missing

7

   

Mutational p53

   

0.001#

 Low expressiona

196

133

90

 

 High expressionb

165

64

74

 

 Missing

15

   

VEGF

   

0.167#

 Low expressiona

302

165

147

 

 High expressionb

64

38

26

 

 Missing

10

   
  1. p -values and #p -values were calculated with the chi-square test and continuity correlation, respectively
  2. aLow expression represented -, +, ++ staining index in IHC examination
  3. bHigh expression represented +++, ++++ staining index in IHC examination