Skip to main content

Table 5 Univariate analyses of prognostic factors in breast cancer using a Cox regression model

From: ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

  

Univariate analyses (OS)

Univariate analyses (LRFS)

No. of patients

p

EXP(B) (SE)

p

EXP(B) (SE)

ALG3

 

< 0.001

2.702 (0.180)

0.013

1.739 (0.147)

 Low expression

203

    

 High expression

173

    

Age

 

0.339

1.181 (1.174)

0.350

0.8698 (0.151)

  ≤ 50

225

    

  > 50

151

    

Stage (AJCC)

 

< 0.001

1.851 (0.176)

0.352

1.146 (0.146)

 I ~ II

188

    

 III

188

    

T

 

0.098

1.384 (0.196)

0.620

1.091 (0.175)

 T1 ~ T2

290

    

 T3 ~ T4

86

    

N

 

< 0.001

1.991 (0.174)

0.022

1.397 (0.146)

 N0 ~ N2

205

    

 N2 ~ N3

171

    

Histological grade

     

 1(indicator)

108

    

 2

179

0.021

1.644 (0.216)

0.065

0.917 (0.167)

 3

89

< 0.001

3.301 (0.247)

0.047

1.483 (0.198)

ER

 

< 0.001

0.444 (0.1745)

< 0.001

0.445 (0.148)

 Negative

169

    

 Positive

207

    

 Missing

0

    

PR

 

< 0.001

0.496 (0.174)

< 0.001

0.430 (0.147)

 Negative

124

    

 Positive

252

    

 Missing

0

    

HER2

 

0.008

1.582 (0.172)

< 0.001

1.729 (0.147)

 Negative

211

    

 Positive

165

    

 Missing

0

    

Ki67

 

< 0.001

2.006 (0.180)

< 0.001

3.547 (0.149)

 Low expressiona

281

    

 High expressionb

88

    

 Missing

7

    

Mutational P53

 

< 0.001

2.139 (0.177)

< 0.001

2.695 (0.150)

 Low expressiona

196

    

 High expressionb

165

    

 Missing

15

    

VEGF

 

0.853

1.042 (0.222)

0.128

1.315 (0.180)

 Low expressiona

302

    

 High expressionb

64

    

 Missing

10

    
  1. aLow expression represented -, +, ++ staining index in IHC examination
  2. bHigh expression represented +++, ++++ staining index in IHC examination
Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us