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Table 5 Univariate analyses of prognostic factors in breast cancer using a Cox regression model

From: ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer

   Univariate analyses (OS) Univariate analyses (LRFS)
No. of patients p EXP(B) (SE) p EXP(B) (SE)
ALG3   < 0.001 2.702 (0.180) 0.013 1.739 (0.147)
 Low expression 203     
 High expression 173     
Age   0.339 1.181 (1.174) 0.350 0.8698 (0.151)
  ≤ 50 225     
  > 50 151     
Stage (AJCC)   < 0.001 1.851 (0.176) 0.352 1.146 (0.146)
 I ~ II 188     
 III 188     
T   0.098 1.384 (0.196) 0.620 1.091 (0.175)
 T1 ~ T2 290     
 T3 ~ T4 86     
N   < 0.001 1.991 (0.174) 0.022 1.397 (0.146)
 N0 ~ N2 205     
 N2 ~ N3 171     
Histological grade      
 1(indicator) 108     
 2 179 0.021 1.644 (0.216) 0.065 0.917 (0.167)
 3 89 < 0.001 3.301 (0.247) 0.047 1.483 (0.198)
ER   < 0.001 0.444 (0.1745) < 0.001 0.445 (0.148)
 Negative 169     
 Positive 207     
 Missing 0     
PR   < 0.001 0.496 (0.174) < 0.001 0.430 (0.147)
 Negative 124     
 Positive 252     
 Missing 0     
HER2   0.008 1.582 (0.172) < 0.001 1.729 (0.147)
 Negative 211     
 Positive 165     
 Missing 0     
Ki67   < 0.001 2.006 (0.180) < 0.001 3.547 (0.149)
 Low expressiona 281     
 High expressionb 88     
 Missing 7     
Mutational P53   < 0.001 2.139 (0.177) < 0.001 2.695 (0.150)
 Low expressiona 196     
 High expressionb 165     
 Missing 15     
VEGF   0.853 1.042 (0.222) 0.128 1.315 (0.180)
 Low expressiona 302     
 High expressionb 64     
 Missing 10     
  1. aLow expression represented -, +, ++ staining index in IHC examination
  2. bHigh expression represented +++, ++++ staining index in IHC examination