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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR)

Fig. 2

CDA and TYMP expression correlated with EMT pathway. a CDA and TYMP expression increased after TGF-β induced EMT transition in A549 and H358 cells, which is showed by immunoblotting (b) CDA and TYMP decreased after TGFβ inhibitor SB431542 induced MET transition. c Correlation matrix between CDA, TYMP expression and EMT transcription factors among lung adenocarcinoma from TCGA database. d, e Correlatin analysis between EMT status and CDA expression based on single cell sequencing of lung adenocarcinoma patient PDX samples. Ordinary two-way ANOVA was used for significance anlysis (*P < .05, **P < .01, ***P < .001, ****P < .0001; n.s., not significant)

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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