Fig. 5

5′-DFCR at recovery day 2 after schedule-dependent treatment induced persistent DNA damage. Accumulation DNA damage within each cell cycle phase was determined in F/S-low and F/S-high cells separately. Cell cycle phases and H2AX phosphorylation levels were gated as described in supplementary Figure S8. Basal ɣH2AX was set at 10% as ɣH2AX high in untreated controls and used for normalization among experiments as described in the material and methods section. Data are represented as mean ± SD (N = 2)